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Urologiia ; (1): 114-118, 2024 Mar.
Article in Russian | MEDLINE | ID: mdl-38655779

ABSTRACT

Clinical cases of three patients with neurogenic lower urinary tract dysfunction, complicated by chronic urinary tract infection are presented in the article. All patients underwent clean intermittent catheterization and, in order to prevent symptomatic lower urinary tract infections, received bacteriophage therapy with a clinically proven positive effect. During 3 months follow-up, there were no episodes of urinary tract infection. A change in the concentration of uropathogens and restoration of sensitivity to a number of antimicrobial drugs were observed. Although phage therapy in urology requires further clinical research, it provides an additional strategy to treat urinary tract infections considering an increase in antibiotic resistance.


Subject(s)
Phage Therapy , Urinary Tract Infections , Humans , Urinary Tract Infections/therapy , Urinary Tract Infections/etiology , Male , Phage Therapy/methods , Middle Aged , Female , Bacteriophages , Urinary Bladder, Neurogenic/therapy , Adult , Aged , Recurrence
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