ABSTRACT
The natural immunity status in different age groups was investigated. The positive rate of HI antibody under the age of 4 was less than 25%. The natural immunity level increased gradually with age and the positive rate of the antibody reached 80% among the group aged 13-25. Rate of seroconversion was 100% in any age group one month after immunization, and GMT rose from 13.33 to 243.16. It was suggested that immunogenicity of domestic attenuated live rubella vaccine BRD II was satisfactory. For the population with positive-antibody before immunization, the total GMT rose from 189.59 to 259.00 after vaccination and the difference between immunization before and after was highly significant. According to the above result, we suggested that the vaccination strategy for rubella among young children and women of child-bearing age should be implemented.
Subject(s)
Rubella Vaccine/immunology , Rubella/prevention & control , Vaccination , Adolescent , Adult , Antibodies, Viral/blood , Child , Child, Preschool , Female , Hemagglutination Inhibition Tests , Humans , Infant , Male , Rubella virus/immunologyABSTRACT
A study on polio virus in pond foul water of town and counties in Lian Yun Gang city which had a reported case of polio. Foul water was examined by 1% NaCl-AlCl3 precipitated method quarterly during 1993-1995, to observe the cyclic development of the virus. Results showed that the isolation rate of polio virus was 57.95% with 21 strains of 18 PV I, 1 PV II and 2 PV III and 30 strains of NPEV (31.09%). In view of PV I as main epidemic strain in our country, and related strains to sabin was confirmed using RT-PCR. The above data suggested that polio virus in the pond water had been replaced by relative strains of sabin.
Subject(s)
Poliovirus/isolation & purification , Water Microbiology , China , Polymerase Chain ReactionABSTRACT
Comprehensively, this paper evaluated the actual vaccination coverage rates in Jiangsu province, using geometric averages to weigh vaccination coverage rates through a) regular and irregular investigation b) conventional report rates and c) registration rates of children at the right age of vaccination. Results showed that the comprehensive method of using vaccination coverage rates for evaluation was better than the conventioned index which had been used before.
