The Galactagogue Effect of Maternal Ingestion of Corn-Based Preparations: A Preliminary Study.

Background: Low human milk production frequently occurs in mothers of premature children with low birth weights who require intensive care. Research Aims: To investigate whether corn-based preparations increase human milk production in women with insufficient milk volumes. Method: This was an intervention study evaluated whether there was an increase in human milk production after a mother's consumption of corn-based preparations. The participants included women with hypogalactia and mothers of infants in neonatal and pediatric intensive care units. The corn-based preparations included green corn cakes and sweet hominies. A total of 35 mother-infant pairs participated in this study. Each mother served as their own control. The study took place over 2 weeks, and data were collected at baseline and after the intervention. At baseline, a socioeconomic questionnaire was used to collect information regarding maternal food consumption, volume of milk expressed, and infant weight and length. All evaluations, except for questionnaire administration, were performed during the intervention phase, when the lactating women ingested the corn-based preparations. Results: A significantly higher average volume of milk was expressed in the intervention period (397.6 ± 182.6 mL/day) compared to baseline (343.6 ± 155.8 mL/day) on the paired t-test (p < 0.001) analysis. Neither energy nor macronutrients consumed correlated with milk volume. Conclusion: The tested corn-based preparations acted as galactagogues and could be used to stimulate milk production in lactating women.

Dietary Selenium Intake and Type-2 Diabetes: A Cross-Sectional Population-Based Study on CUME Project.

Background and Aim: Previous studies have suggested that the specific association between selenium (Se) and diabetes remains unclear. This study aimed to investigate the association between dietary Se and type-2 diabetes (T2D) in the Brazilian cohort [Cohort of Universities of Minas Gerais (CUME)]. Methods and Results: This cross-sectional study was conducted with a large sample comprising 4,106 participants of the CUME project, a concurrent open cohort restricted to a highly educated population group, composed of graduates of federal institutions of higher education located in the State of Minas Gerais, Brazil. Data on socioeconomic and dietary characteristics, as well as anthropometric measures, were collected from each subject for analysis. The sample was classified into energy-adjusted tertiles of dietary Se intake (µg/day). Differences in the continuous data were evaluated by the Kruskal-Wallis H-test (abnormal data), and the χ2-test assessed differences in qualitative data. As there was no relationship between T2D and Se intake in the bivariate analysis, multivariate analysis was not performed. The prevalence of T2D in the studied population was 2.8%. The mean age was 36 years. Regarding gender, 1,209 are males and 2,807 are females. Among females, the mean Se intake was 165.12 µg/day and the mean intake was 157.4 µg/day. Among males, it was 168.4 µg/day. Significant differences were observed across all Se intake tertiles in terms of age, gender, activity level, alcohol intake, energy intake, sugar, carbohydrates, lipids, fiber, and energy-adjusted meat intake. However, no significant differences were observed across all Se intake tertiles in terms of BMI, smoking status, and T2D. The results indicated that there was no significant association between dietary Se intake and the prevalence of T2D. Conclusion: Dietary Se intake was not associated with the prevalence of T2D, despite the high intake of this micronutrient in the sample. These results contradict studies that identified the association between Se intake and T2D, with values of Se intake much lower than those observed in this study. Thus, this relationship seems to remain controversial.