ABSTRACT
Osteomyelitis is an inflammatory condition of bone secondary to an infectious process. Osteomyelitis is usually clinically diagnosed with support from imaging and laboratory findings. Bone biopsy and microbial cultures offer definitive diagnosis. Plain film radiography should be performed as initial imaging, but sensitivity is low in the early stages of disease. Magnetic resonance imaging with and without contrast media has a higher sensitivity for identifying areas of bone necrosis in later stages. Staging based on major and minor risk factors can help stratify patients for surgical treatment. Antibiotics are the primary treatment option and should be tailored based on culture results and individual patient factors. Surgical bony debridement is often needed, and further surgical intervention may be warranted in high-risk patients or those with extensive disease. Diabetes mellitus and cardiovascular disease increase the overall risk of acute and chronic osteomyelitis.
Subject(s)
Anti-Bacterial Agents/therapeutic use , Debridement , Osteomyelitis/therapy , Humans , Magnetic Resonance Imaging , Osteomyelitis/diagnostic imaging , Radiography , Risk Factors , Severity of Illness IndexABSTRACT
The first meta-analysis to focus on viscous dietary fiber in T2D suggests a potential role for this supplement in improving glycemic control.
Subject(s)
Diabetes Mellitus, Type 2 , Biomarkers , Blood Glucose , Diabetes Mellitus, Type 2/drug therapy , Dietary Fiber , Dietary Supplements , HumansABSTRACT
We typically take a blood pressure within 3 minutes of a patient rising from a supine to a standing position. But is that too long?
Subject(s)
Blood Pressure Determination/methods , Hypotension, Orthostatic/diagnosis , Standing Position , Dizziness/etiology , Humans , Hypotension, Orthostatic/physiopathology , Supine Position , Time FactorsABSTRACT
The author list for the June 2019 PURL ("A better approach to the diagnosis of PE." J Fam Pract. 2019;68:286,287,295) should have read: Andrew H. Slattengren, DO; Shailendra Prasad, MBBS, MPH; David C. Bury, DO; Michael M. Dickman, DO; Nick Bennett, DO; Ashley Smith, MD; Robert Oh, MD, MPH, FAAFP; Robert Marshall, MD, MPH, MISHM, FAAFP.
