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1.
Z Kinder Jugendpsychiatr Psychother ; 47(3): 204-210, 2019 May.
Article in German | MEDLINE | ID: mdl-30375938

ABSTRACT

Experiences with an intercultural training for professionals from child-welfare services working with children and adolescents following child abuse and neglect Abstract. Background: As part of a multicenter study evaluating measures to improve access to evidenced-based treatment for children and adolescents following child abuse and neglect, we introduced and evaluated migration-adapted services, including a one-day intercultural training. Key issues were the dissemination of information concerning migration and acculturation, trauma and mental health to immigrant families as well as the development of exercises on intercultural competence and culturally sensitive work. Method: Near the end of the research project we gathered experiences and opinions concerning the work with immigrant families using an online survey in a subgroup of case managers working in the project (professionals in child-welfare services). This article presents two case report illustrating the practical relevance of the training's content. Results: Overall, the training was rated positively. In the opinion of the case managers, especially language barriers and cultural diversity should be considered while working with immigrant families. The case reports show that the training sensitized and supported the case managers supported the case managers when dealing with differing illness concepts, differing illness concepts, culture-sensitive assessment, or work with language mediators. Conclusions: The case management work also demonstrated the limitations of the psychosocial care system; the further dissemination of intercultural knowledge is important.


Subject(s)
Child Abuse/psychology , Child Welfare , Communication Barriers , Cultural Competency/education , Emigrants and Immigrants/psychology , Adolescent , Child , Cultural Diversity , Humans
3.
Biofactors ; 38(1): 53-8, 2012.
Article in English | MEDLINE | ID: mdl-22311849

ABSTRACT

The antioxidant status of coenzyme Q10 (CoQ10) was investigated in plasma, erythrocytes, and platelets of juvenile patients with anorexia nervosa. Blood for analysis of the CoQ10 status was taken from 16 juvenile patients suffering from anorexia nervosa (restricting form) at the time point of admission to the hospital and at discharge after about 12 weeks. Plasma and blood cells isolated by a density gradient were stored at -84 °C until analysis. CoQ10 concentration and redox status were measured by high pressure liquid chromatography with electrochemical detection and internal standardization. The improvement of physical health during the hospital refeeding process was followed up by the body mass index (BMI). The antioxidant status of plasma CoQ10 in juvenile patients suffering from anorexia nervosa indicated no abnormalities in comparison to healthy controls. However, the decreased concentration of CoQ10 observed in platelets at the time point of hospital admission may represent mitochondrial CoQ10 depletion. This initial deficit improved during the hospital refeeding process. The platelet CoQ10 concentration showed a positive correlation to the BMI of the patients.


Subject(s)
Anorexia Nervosa/blood , Blood Platelets/metabolism , Erythrocytes/metabolism , Ubiquinone/analogs & derivatives , Adolescent , Biomarkers/blood , Body Mass Index , Child , Female , Hospitalization , Humans , Male , Statistics, Nonparametric , Ubiquinone/blood
4.
Horm Res ; 70(1): 51-7, 2008.
Article in English | MEDLINE | ID: mdl-18493150

ABSTRACT

BACKGROUND/AIMS: The aim of this study was to analyze thyroid hormones in female adolescents with obesity and anorexia nervosa (AN) before and after normalization of weight. METHODS: Thyroid-stimulating hormone (TSH), fT3, and fT4 were determined in 100 obese girls, 32 normal-weight girls and 20 girls with AN aged 14-18 years at baseline and 1 year later. Additionally, leptin, insulin, and the insulin resistance index HOMA were analyzed in the obese and normal-weight girls. RESULTS: TSH and fT3 levels of girls with AN were significantly lower compared to TSH concentrations of normal-weight girls, while TSH and fT3 levels of the obese girls were significantly higher. The 21 obese females with weight loss >5% demonstrated a significant decrease in fT3 and TSH, while the 9 adolescents with AN and weight gain >5% showed a significant increase in fT3 and TSH. Insulin and HOMA were not significantly correlated to TSH, fT3 and fT4, while leptin was correlated to TSH and fT3 in both cross-sectional and longitudinal analysis. CONCLUSIONS: Thyroid function seems to be reversibly related to weight status with increased TSH and fT3 concentrations in obesity and decreased TSH and fT3 levels in AN. We hypothesize that leptin may be the link between weight status and TSH.


Subject(s)
Anorexia Nervosa/blood , Body Weight , Obesity/blood , Thyrotropin/blood , Thyroxine/blood , Triiodothyronine/blood , Adolescent , Anorexia Nervosa/therapy , Female , Follow-Up Studies , Humans , Insulin/blood , Insulin Resistance , Leptin/blood , Obesity/therapy
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