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Nuklearmedizin ; 54(3): 125-30, 2015.
Article in German | MEDLINE | ID: mdl-25421138

ABSTRACT

There is no clear standard therapy for patients with radioactive iodine (131I)-refractory locally advanced or metastatic differentiated thyroid cancer. The therapeutic options for this indication have expanded with the recently approved multiple kinase inhibitor sorafenib. Recommendations for the definition and the management of iodine refractory patients were worked up by an interdisciplinary expert panel, consisting of endocrine surgeons, medical oncologists and nuclear medicine specialists.


Subject(s)
Antineoplastic Agents/administration & dosage , Iodine Radioisotopes/therapeutic use , Niacinamide/analogs & derivatives , Phenylurea Compounds/administration & dosage , Practice Guidelines as Topic , Thyroid Neoplasms/diagnosis , Thyroid Neoplasms/therapy , Antineoplastic Agents/adverse effects , Chemoradiotherapy/standards , Evidence-Based Medicine , Germany , Humans , Medical Oncology/standards , Niacinamide/administration & dosage , Niacinamide/adverse effects , Phenylurea Compounds/adverse effects , Protein Kinase Inhibitors/administration & dosage , Protein Kinase Inhibitors/adverse effects , Radiopharmaceuticals/therapeutic use , Sorafenib , Treatment Failure , Treatment Outcome
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