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1.
Magn Reson Med ; 79(6): 3256-3266, 2018 06.
Article in English | MEDLINE | ID: mdl-28983969

ABSTRACT

PURPOSE: The goal of this study was to devise a gradient system for MRI in humans that reconciles cutting-edge gradient strength with rapid switching and brings up the duty cycle to 100% at full continuous amplitude. Aiming to advance neuroimaging and short-T2 techniques, the hardware design focused on the head and the extremities as target anatomies. METHODS: A boundary element method with minimization of power dissipation and stored magnetic energy was used to design anatomy-targeted gradient coils with maximally relaxed geometry constraints. The design relies on hollow conductors for high-performance cooling and split coils to enable dual-mode gradient amplifier operation. With this approach, strength and slew rate specifications of either 100 mT/m with 1200 mT/m/ms or 200 mT/m with 600 mT/m/ms were reached at 100% duty cycle, assuming a standard gradient amplifier and cooling unit. RESULTS: After manufacturing, the specified values for maximum gradient strength, maximum switching rate, and field geometry were verified experimentally. In temperature measurements, maximum local values of 63°C were observed, confirming that the device can be operated continuously at full amplitude. Testing for peripheral nerve stimulation showed nearly unrestricted applicability in humans at full gradient performance. In measurements of acoustic noise, a maximum average sound pressure level of 132 dB(A) was determined. In vivo capability was demonstrated by head and knee imaging. Full gradient performance was employed with echo planar and zero echo time readouts. CONCLUSION: Combining extreme gradient strength and switching speed without duty cycle limitations, the described system offers unprecedented options for rapid and short-T2 imaging. Magn Reson Med 79:3256-3266, 2018. © 2017 International Society for Magnetic Resonance in Medicine.


Subject(s)
Image Processing, Computer-Assisted/methods , Magnetic Resonance Imaging/methods , Brain/diagnostic imaging , Equipment Design , Humans , Knee/diagnostic imaging , Male , Nonlinear Dynamics , Phantoms, Imaging , Temperature
2.
MAGMA ; 30(5): 473-488, 2017 Oct.
Article in English | MEDLINE | ID: mdl-28444504

ABSTRACT

OBJECTIVES: The accuracy and precision of the parallel RF excitations are highly dependent on the spatial and temporal fidelity of the magnetic fields involved in spin excitation. The consistency between the nominal and effective fields is typically limited by the imperfections of the employed hardware existing both in the gradient system and the RF chain. In this work, we experimentally presented highly improved spatially tailored parallel excitations by turning the native hardware accuracy challenge into a measurement and control problem using an advanced field camera technology to fully correct parallel RF transmission experiment. MATERIALS AND METHODS: An array of NMR field probes is used to measure the multiple channel RF pulses and gradient waveforms recording the high power RF pulses simultaneously with low frequency gradient fields on equal time basis. The recorded waveforms were integrated in RF pulse design for gradient trajectory correction, time imperfection compensation and introduction of iterative RF pre-emphasis. RESULTS: Superior excitation accuracy was achieved. Two major applications were presented at 7 Tesla including multi-dimensional tailored RF pulses for spatially selective excitation and slice-selective spoke pulses for [Formula: see text] mitigation. CONCLUSION: Comprehensive field monitoring is a highly effective means of correcting for the field deviations during parallel transmit pulse design.


Subject(s)
Magnetic Resonance Imaging/methods , Radio Waves , Algorithms , Equipment Design , Humans , Imaging, Three-Dimensional , Magnetic Fields , Magnetic Resonance Imaging/instrumentation , Magnetic Resonance Imaging/statistics & numerical data , Models, Theoretical , Phantoms, Imaging
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