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1.
Rev. bras. oftalmol ; 77(6): 353-355, nov.-dez. 2018. graf
Article in English | LILACS | ID: biblio-985309

ABSTRACT

Abstract Herein we report a case of juvenile xantogranuloma, an inflammatory disease more commonly diagnosed during childhood and is characterized by cutaneous and ocular manifestations. Iris is the main target, presenting as local or diffuse yellowish lesions. Iris involvement may precipitate not only glaucoma but also amblyopia. Treatment is based on corticosteroids therapy, either local or systemic aiming disease control.


Resumo É relatado um caso raro de xantogranuloma juvenil, doença de natureza inflamatória diagnosticada mais frequentemente na infância, com manifestações cutâneas e oculares. A íris é o principal sítio extracutâneo da doença, apresentando-se como lesão amarelada, difusa ou localizada. O acometimento iriano pode acarretar surgimento de glaucoma, além de ambliopia. O manejo clínico da lesão ocular no presente caso foi baseado no necessidade no uso contínuo de corticoide tópico e sistêmico para estabilização da doença.


Subject(s)
Humans , Female , Infant , Xanthogranuloma, Juvenile/complications , Iris Diseases/etiology , Iris Diseases/drug therapy , Iris Diseases/diagnostic imaging , Ophthalmoscopy , Scalp/pathology , Scalp Dermatoses/etiology , Dexamethasone/administration & dosage , Hyphema , Prednisolone/administration & dosage , Glaucoma , Ultrasonography , Facial Dermatoses/etiology , Slit Lamp Microscopy , Fundus Oculi
2.
Saudi J Ophthalmol ; 30(2): 113-6, 2016.
Article in English | MEDLINE | ID: mdl-27330387

ABSTRACT

PURPOSE: The aim of this study was to determine the frequency of clinically unsuspected ocular surface squamous neoplasia (OSSN) in cases of biopsied pterygium (PT). METHODS: We reviewed 15,016 cases presented at the Henry C. Witelson Ocular Pathology Laboratory during the period 1993-2013. All cases with a clinical diagnosis of PT were included. Histopathological diagnoses were reviewed and demographic data were retrieved from histopathological request forms. All cases associated with OSSN were re-evaluated independently by two ocular pathologists. The classification of OSSN in PT cases was made based on the Armed Forces Institute of Pathology (AFIP) recommendations. RESULTS: Two hundred and fifteen cases were diagnosed clinically as PT (1.43%) and 54% were from male patients. The average age at diagnosis was 53.4 ± 15.5 years. OSSN was identified in five cases (2.33%), and four of these cases were from female patients (80%). The average age of patients with PT and OSSN was similar to PT patients without OSSN (P > 0.05). Cases with OSSN were diagnosed as conjunctival intraepithelial neoplasia (CIN) I (60%), CIN II (20%), and CIN III (20%). There was complete agreement between the two pathologists (100%). CONCLUSIONS: The relatively high rate of dysplasia in a low ultraviolet light index area challenges the main cause of this disease in our population, a hypothesis that should be evaluated in future studies. We suggest that all PT samples should be sent for histopathological evaluation even in areas with low ultraviolet light index.

3.
J Ophthalmol ; 2016: 2380764, 2016.
Article in English | MEDLINE | ID: mdl-27213051

ABSTRACT

Purpose. To describe the histopathological features of vitreous samples obtained after vitrectomy surgery from diabetic and nondiabetic patients. Methods. Vitreous specimens from 137 patients who underwent vitrectomy for different clinical conditions were analysed. All samples were centrifuged and each resulting pellet was fixed and processed as part of routine paraffin section histopathology. The histopathological features were categorized in a semiquantitative fashion. The samples from diabetic and nondiabetic patients were compared. Results. The 125 included patients (58 diabetic, 60% males) were aged 64.2 ± 13.9 years. The presence of hemorrhage, inflammatory cells, and histiocytes was significantly higher in the diabetic group (P < 0.001, P = 0.028, and P = 0.016, resp.), showing more vessels (P < 0.001) and ghost vessels (P = 0.049). The presence of inflammatory cells was the feature with the highest sensitivity for detecting diabetes mellitus (98%) and also the highest negative predictive value (89%). In the multivariate analysis, three variables emerged as independent significant predictors of diabetes in vitrectomy samples: hemorrhage, endothelial-lined vessels, and age (P < 0.001, P < 0.001, and P = 0.019, resp.). Conclusions. Different histopathological features can be found in vitreous samples from diabetic patients. Analysis of vitrectomy samples may serve as a tool for diabetes management.

4.
Saúde debate ; 37(98): 437-445, jul.-set. 2013.
Article in Portuguese | LILACS-Express | LILACS | ID: lil-700159

ABSTRACT

A criação de um espaço democrático de participação na condução do Sistema Único de Saúde (SUS) constituiu indubitável conquista dos brasileiros. O pleno exercício deste direito implica, no entanto, no conhecimento do próprio direito, dos espaços e dos mecanismos de participação, que permitam uma ação autônoma. No presente trabalho avalia-se o grau de conhecimento nos diversos segmentos sociais acerca da questão. Foram entrevistados usuários e trabalhadores do SUS, além de membros dos Conselhos de Saúde. Os resultados demonstram grande desinformação dos usuários, dos novos conselheiros e da maioria dos trabalhadores, em contraste com os gestores e os conselheiros com mais tempo no cargo.


The creation of a democratic space for participation in the conduction of the Sistema Único de Saúde ( SUS) - Brazilian Public Health Care System - was undoubtedly an achievement for Brazilians. Full exercise of this right implies, however, knowledge of the right itself, spaces and mechanisms for participation, allowing for autonomous action. The present study evaluates the degree of knowledge in the various social segments on this issue. Users and workers of SUS health care units were interviewed as well as members of Health Councils. Results show misinformation from most councilors and health workers when compared to managers and advisors who have worked longer in their positions.

5.
Plast Surg Int ; 2012: 973240, 2012.
Article in English | MEDLINE | ID: mdl-23304489

ABSTRACT

Goals/Background. To evaluate children's growth in the first year of life, who have cleft palate and lip, without the use of palatal plates. Materials/Method. Chart review was conducted, retrospectively, in the Center for Integral Assistance of Cleft Lip and Palate (CAIF), in Brazil, between 2008 and 2009. Results for both genders were compared to the data published by the World Health Organization (WHO) regarding average weight gain in children during their first year of life. Results. Patients with syndromic diagnosis and with cleft classified as preforamen were excluded, resulting in a final number of 112 patients: 56 male and 56 female. Similar patterns were seen comparing the two genders. Although it was observed weight gain below the average until the 11th month in male patients and until 9 months in female patients, both genders remained at the 50th percentile (p50) and improved after the 4th month of age for boys and the 9th month of age for girls. Conclusion. Children with cleft palate weigh less than regular children during their first months of life. At the end of the first year, weight gain is similar comparing normal and affected children. However, factors that optimized weight gain included choosing the best treatment for each case, proper guidance, and multiprofessional integrated care.

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