ABSTRACT
Benign polyps containing atypical stromal cells are described at many anatomical sites and some such lesions have been shown to contain intracytoplasmic actin-rich inclusions, believed to represent deranged filament metabolism in proliferating myofibroblastic cells. We present a case of an atypical cervical polyp with intracytoplasmic inclusions, occurring in a 23 year old female, and provide support for the proposal that these inclusions are composed of actin filaments, identical to those initially reported in infantile digital fibromatosis. This report emphasises the need to recognise the benign nature of such stromal proliferations and expands the range of myofibroblastic lesions in which actin inclusions may occur. Characterisation of the inclusions will provide further insight into the complexities of actin metabolism.
Subject(s)
Inclusion Bodies/pathology , Polyps/pathology , Uterine Cervical Neoplasms/pathology , Actins/analysis , Adult , Desmin/analysis , Female , Humans , Immunohistochemistry , Inclusion Bodies/chemistry , Inclusion Bodies/ultrastructure , Polyps/chemistry , Polyps/ultrastructure , Uterine Cervical Neoplasms/chemistry , Uterine Cervical Neoplasms/ultrastructureABSTRACT
Air embolism is an uncommon cause of cardiovascular collapse in obstetric surgery. A case is presented in which air was introduced through the open venous sinuses of a partially separated placenta during a delivery by caesarean section. The mechanism of death, methods of monitoring for air embolus, and treatment of embolism are discussed.
