ABSTRACT
OBJECTIVE: To evaluate the performance of the epoc hand-held analyzer against the RAPIDPoint 500 blood gas analyzer and laboratory analyzers where applicable. METHODS: Venous or arterial whole blood samples collected in balanced heparinized syringes were obtained from 69 patients (35 females, 34 males) predominantly (77%) from the surgical unit and intensive care unit (ICU). Method comparison was performed for all analytes on the epoc System against the RAPIDPoint 500 Blood gas analyzer or laboratory analyzers where applicable. Results: Mean bias was <5% for blood gases, electrolytes, lactate and glucose. Hematocrit showed a bias of -6.76% (95% CI â= â-8.91, - 4.61) compared to the HemataSTAT-II method, whereas calculated total hemoglobin showed a bias of 1.51% (95% CI â= â-1.04, 4.06) against the Sysmex XN-10 hematology analyzer. Creatinine showed the largest bias relative to laboratory analyzers, Abbott Architect c8000 Jaffe method (13.54%, 95% CI â= â5.43, 21.65) and Roche Cobas c702 enzymatic method (30.01%, 95% CI â= â12.64, 47.38). Conclusions: The epoc system is fit for use in the surgical and ICU setting for the measurement of all analytes except for creatinine.
ABSTRACT
OBJECTIVE: To evaluate the analytical performance of the Nova StatSensor creatinine meter. DESIGN AND METHODS: Imprecision, linearity, patient correlation and interference studies were completed. RESULTS: Total imprecision was 4.5-9.1%CV and a linear measurement range of 93-863 micromol/L (1.05-9.76 mg/dL) was verified. Whole blood creatinine results correlated well with laboratory plasma measurements (R(2)=0.9328) but exhibited a negative proportional bias. In vitro, high levels of creatine and urea falsely elevated creatinine measurement. CONCLUSIONS: The creatinine meter provides reliable measurement across a clinically relevant range and has potential use in point-of-care testing.