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1.
Sensors (Basel) ; 19(17)2019 Aug 25.
Article in English | MEDLINE | ID: mdl-31450666

ABSTRACT

In recent years, physiological features have gained more attention in developing models of personal thermal comfort for improved and accurate adaptive operation of Human-In-The-Loop (HITL) Heating, Ventilation, and Air-Conditioning (HVAC) systems. Pursuing the identification of effective physiological sensing systems for enhancing flexibility of human-centered and distributed control, using machine learning algorithms, we have investigated how heat flux sensing could improve personal thermal comfort inference under transient ambient conditions. We have explored the variations of heat exchange rates of facial and wrist skin. These areas are often exposed in indoor environments and contribute to the thermoregulation mechanism through skin heat exchange, which we have coupled with variations of skin and ambient temperatures for inference of personal thermal preferences. Adopting an experimental and data analysis methodology, we have evaluated the modeling of personal thermal preference of 18 human subjects for well-known classifiers using different scenarios of learning. The experimental measurements have revealed the differences in personal thermal preferences and how they are reflected in physiological variables. Further, we have shown that heat exchange rates have high potential in improving the performance of personal inference models even compared to the use of skin temperature.


Subject(s)
Body Temperature Regulation/physiology , Machine Learning , Monitoring, Physiologic , Skin Physiological Phenomena , Air Conditioning , Algorithms , Hot Temperature , Humans , Skin Temperature/physiology , Thermosensing/physiology , Ventilation
2.
Sci Total Environ ; 635: 1215-1224, 2018 Sep 01.
Article in English | MEDLINE | ID: mdl-29710576

ABSTRACT

The thermal energy represents a significant portion of energy potential in municipal wastewater and may be recovered as electricity by a thermoelectric generator (TEG). Converting heat to all-purpose electricity by TEG has been demonstrated with large heat gradients, but its application in waste heat recovery from wastewater has not been well evaluated. Herein, a bench-scale Bi2Te3-based waste heat recovery system was employed to generate electricity from a low temperature gradient through a combination of experiments and mathematical modeling. With an external resistance of 7.8â€¯Ω and a water (hot side) flow rate of 75 mL min-1, a maximum normalized energy recovery of 4.5 × 10-4 kWh m-3 was achieved under a 2.8 °C temperature gradient (ΔT). Model simulation indicated a boost in both power output and energy conversion efficiency from 0.76 mW and 0.13% at ΔT = 2.8 °C to 61.83 mW and 1.15% at ΔT = 25 °C. Based on the data of two-year water/air temperature obtained from the Christiansburg Wastewater Treatment Plant, an estimated energy generation of 1094 to 70,986 kWh could be expected annually with a saving of $163 to $6076. Those results have revealed a potential for TEG-centered direct electricity generation from low-grade heat towards enhanced resource recovery from wastewater and encouraged further exploration of this approach.

3.
IEEE Trans Biomed Eng ; 64(7): 1631-1637, 2017 07.
Article in English | MEDLINE | ID: mdl-28113229

ABSTRACT

A new thin-filmed perfusion sensor was developed using a heat flux gauge, thin-film thermocouple, and a heating element. This sensor, termed "CHFT+," is an enhancement of the previously established combined heat flux-temperature (CHFT) sensor technology predominately used to quantify the severity of burns [1]. The CHFT+ sensor was uniquely designed to measure tissue perfusion on explanted organs destined for transplantation, but could be functionalized and used in a wide variety of other biomedical applications. Exploiting the thin and semiflexible nature of the new CHFT+ sensor assembly, perfusion measurements can be made from the underside of the organ-providing a quantitative indirect measure of capillary pressure occlusion. Results from a live tissue test demonstrated, for the first time, the effects of pressure occlusion on an explanted porcine kidney. CHFT+ sensors were placed on top of and underneath 18 kidneys to measure and compare perfusion at perfusate temperatures of 5 and 20 °C. The data collected show a greater perfusion on the topside than the underside of the specimen for the length of the experiment. This indicates that the pressure occlusion is truly affecting the perfusion, and, thus, the overall preservation of explanted organs. Moreover, the results demonstrate the effect of preservation temperature on the tissue vasculature. Focusing on the topside perfusion only, the 20 °C perfusion was greater than the 5 °C perfusion, likely due to the vasoconstrictive response at the lower perfusion temperatures.


Subject(s)
Heating/instrumentation , Kidney Transplantation , Organ Preservation/adverse effects , Renal Artery Obstruction/etiology , Renal Artery Obstruction/physiopathology , Renal Artery/physiopathology , Thermography/instrumentation , Animals , Capillary Permeability , Equipment Design , Equipment Failure Analysis , In Vitro Techniques , Renal Artery Obstruction/diagnosis , Reproducibility of Results , Sensitivity and Specificity , Swine , Thermal Conductivity
4.
J Biomech Eng ; 130(5): 051002, 2008 Oct.
Article in English | MEDLINE | ID: mdl-19045509

ABSTRACT

A convenient method for testing and calibrating surface perfusion sensors has been developed. A phantom tissue model is used to simulate the nondirectional blood flow of tissue perfusion. A computational fluid dynamics (CFD) model was constructed in Fluent(R) to design the phantom tissue and validate the experimental results. The phantom perfusion system was used with a perfusion sensor based on clearance of thermal energy. A heat flux gage measures the heat flux response of tissue when a thermal event (convective cooling) is applied. The blood perfusion and contact resistance are estimated by a parameter estimation code. From the experimental and analytical results, it was concluded that the probe displayed good measurement repeatability and sensitivity. The experimental perfusion measurements in the tissue were in good agreement with those of the CFD models and demonstrated the value of the phantom tissue system.


Subject(s)
Biomimetics/instrumentation , Blood Flow Velocity/physiology , Phantoms, Imaging , Rheology/instrumentation , Skin Physiological Phenomena , Skin/blood supply , Biomimetics/methods , Calibration , Equipment Design , Equipment Failure Analysis , Humans , Rheology/methods , Rheology/standards
5.
J Biomech Eng ; 130(6): 061013, 2008 Dec.
Article in English | MEDLINE | ID: mdl-19045542

ABSTRACT

A simple, cost effective, and noninvasive blood perfusion system is tested in animal models. The system uses a small sensor to measure the heat transfer response to a thermal event (convective cooling) imposed on the tissue surface. Heat flux data are compared with a mathematical model of the tissue to estimate both blood perfusion and thermal contact resistance between the tissue and the probe. The perfusion system was evaluated for repeatability and sensitivity using isolated rat liver and exposed rat kidney tests. Perfusion in the isolated liver tests was varied by controlling the flow of the perfusate into the liver, and the perfusion in the exposed kidney tests was varied by temporarily occluding blood flow through the renal artery and vein. The perfusion estimated by the convective perfusion probe was in good agreement with that of the metered flow of the perfusate into the liver model. The liver tests indicated that the probe can be used to detect small changes in perfusion (0.005 ml/ml/s). The probe qualitatively tracked the changes in the perfusion in the kidney model due to occlusion of the renal artery and vein.


Subject(s)
Blood Flow Velocity/physiology , Kidney/physiology , Liver Circulation/physiology , Liver/physiology , Renal Circulation/physiology , Rheology/instrumentation , Anesthesia , Animals , Equipment Design , Equipment Failure Analysis , In Vitro Techniques , Kidney/blood supply , Liver/blood supply , Male , Rats , Rats, Sprague-Dawley , Reproducibility of Results , Rheology/methods , Sensitivity and Specificity
6.
Int J Heat Mass Transf ; 51(23-24): 5740-5748, 2008 Nov 01.
Article in English | MEDLINE | ID: mdl-19885372

ABSTRACT

Non-invasive blood perfusion measurement systems have been developed and tested in a phantom tissue and an animal model. The probes use a small sensor with a laminated flat thermocouple to measure the heat transfer and temperature response to an arbitrary thermal event (convective or conductive) imposed on the tissue surface. Blood perfusion and thermal contact resistance are estimated by comparing heat flux data with a mathematical model of the tissue. The perfusion probes were evaluated for repeatability and sensitivity using both a phantom tissue test stand and exposed rat liver tests. Perfusion in the phantom tissue tests was varied by controlling the flow of water into the phantom tissue test section, and the perfusion in the exposed liver tests was varied by temporarily occluding blood flow through the portal vein. The phantom tissue tests indicated that the probes can be used to detect small changes in perfusion (0.005 ml/ml/s). The probes qualitatively tracked the changes in the perfusion of the liver model due to occlusion of the portal vein.

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