ABSTRACT
We investigated the effect of three types of respiratory support on respiratory parameters in conscious healthy humans. For each type of respiratory support set specific changes in the pattern of volume and temporal parameters. One response to all types of respiratory support was hyperventilating, although varying degrees, and as a consequence, hypocapnia. These changes are not related to the metabolic needs and probably are the result of the interaction mechanisms of automatic and voluntary regulation of breathing movements.
Subject(s)
Pulmonary Ventilation/physiology , Respiration, Artificial/methods , Respiration , Adult , Carbon Dioxide/metabolism , Female , Humans , Hypocapnia/physiopathology , Male , Middle Aged , Young AdultABSTRACT
We did Read CO2 rebreathing tests in 8 adult males. Both at natural breathing, and at self-controlled mechanical ventilation, volunteers increased ventilation proportionally to growth end-tidal PCO2. Inside individual distinctions of responses to CO2 during controlled mechanical ventilation are result of the voluntary motor control.
Subject(s)
Carbon Dioxide/administration & dosage , Pulmonary Ventilation/drug effects , Pulmonary Ventilation/physiology , Respiration/drug effects , Adolescent , Adult , Humans , Male , Middle Aged , Respiration, ArtificialSubject(s)
Carbon Dioxide/physiology , Pulmonary Ventilation/physiology , Respiration , Adolescent , Adult , Aged , Humans , Male , Middle Aged , Respiration, ArtificialSubject(s)
Brain/immunology , Brain/physiopathology , Electronarcosis/methods , Hemodynamics/drug effects , Lung Neoplasms/surgery , Adult , Analgesics, Opioid , Anesthetics, Dissociative , Brain/drug effects , Electric Stimulation , Humans , Ketamine , Lung Neoplasms/immunology , Lung Neoplasms/physiopathologyABSTRACT
Hemodynamics was studied in 60 patients with pronounced initial hypovolemia, urgently operated on for acute gastrointestinal disease under conditions of 4 anesthesia. In contrast to traditional anesthesia, transcranial electric stimulation (TCES) as a component of anesthesia stabilized hemodynamics without increasing the rate and volume of intraoperative infusion therapy. This makes total anesthesia with TCES preferable in urgent operations, particularly in cases when hypovolemia cannot be properly corrected before surgery.
