ABSTRACT
[This corrects the article DOI: 10.1039/C7RA10158A.].
ABSTRACT
OBJECTIVE: The major components of Xingsusan decoction were studied by HPLC-HR-TOF-MS. METHODS: A Welchrom- C18 column (4.6 mm x 250 mm, 5 µm) was used at a flow rate of 1.0 mL/min. The HPLC gradient was acetonitrile-formic acid (99.9: 0.1, V/V) (B) and water-formic acid (99.9:0.1, V/V) (A). HR-MS/MS analysis were carried out using a Micro/TOF-Q II Focus mass spectrometer fitted with an ESI source operating in Auto-MSn mode to obtain fragment ions. TIC chemical profiles of the extract were established in both positive and negative modes. The structures of the known components in Xingsusan decoction were identified by comparing their retention times, molecular weight and CID fragmentation patterns with their corresponding compounds reported in the literature. RESULTS: A total of 52 components were simultaneously detected in Q-TOF/MS. CONCLUSION: This method can be used as reference for other Chinese Medicine formulas study.
Subject(s)
Drugs, Chinese Herbal/chemistry , Acetonitriles , Chromatography, High Pressure Liquid , Chromatography, Liquid , Formates , Tandem Mass SpectrometryABSTRACT
The data of 72 cases of advanced schistosomiasis portal hypertension patients who received surgical treatment were retrospectively analyzed in the Fifth People's Hospital of Changde City from January, 1999 to January, 2011. Postoperative complications occurred in 17 cases, and the rate was 23.6%, including intra-abdominal bleeding in 2 cases, postoperative infection in 5 cases, recent upper gastrointestinal bleeding in 3 cases, massive ascites in 2 cases, persistent fever in 3 cases, and unusual increase of platelets and portal vein thrombosis in 2 cases.
