Fabrication of magnetic carboxyl-functionalized attapulgite/calcium alginate beads for lead ion removal from aqueous solutions.

In the present study, we synthesized an effective Pb(II) adsorbent from magnetic carboxyl-functionalized attapulgite (McAPT) and sodium alginate (Alg) by simple mechanical agitation at room temperature. The novel McAPT@Alg composite was systematically characterized using a number of instrumental techniques, and the effects of adsorbent dosage, initial concentration of Pb(II), adsorption time, pH, and temperature on the adsorption capacity were investigated by performing batch experiments. The obtained results demonstrated that adsorption equilibrium could be reached within 1.5 h, with the maximum adsorption capacity being 471.20 mg g-1 while the temperature was 297.2 K. The experimental data were suitable for application to the Langmuir isotherm model, and the adsorption kinetics agreed with the pseudo-second-order model. More importantly, a Pb(II) removal efficiency of >70% could be achieved after 6× adsorbent recycling, which demonstrated the excellent potential of McAPT@Alg for removing Pb(II) from contaminated water.

Comprehensive analysis on clinical features of Wilson's disease: an experience over 28 years with 133 cases.

OBJECTIVES: Here, we reported our experience over 28 years with 133 cases of patients with Wilson's disease (WD) in order to illustrate the diverse clinical presentation and to improve understanding and early diagnosis of WD. METHODS: We reviewed the medical records of patients with WD at Shengjing Hospital of China Medical University from 1993 to 2011. The clinical manifestations and laboratory findings were analyzed. The diagnosis was based on the presence of Kayser-Fleisher (K-F) rings, low serum copper levels, low serum ceruloplasmin levels, increased urinary copper concentrations before or after penicillamine challenge. RESULTS: Among them, 93 patients mainly presented with hepatic manifestations, 27 with neural abnormalities, and 13 presented with others. Age range at diagnosis was wide (3-74 years, average 13·2 years), and five patients were over 40 years. The oldest one was aged 74 years and presented with neuropsychiatric disorder. The positive rate of K-F rings was 93·0%. The serum ceruloplasmin decreased in 83·6% patients, 24-hour urinary copper increased in 88·1% patients, and serum copper decreased in 68·9% patients. About 79·7% of patients were diagnosed within 6 months, but only 33·1% were diagnosed at their initial medical consultation. There was a substantial delay of up to 15 years. CONCLUSIONS: The clinical manifestation of WD is very diverse and no one feature is completely reliable. Doctors in many fields have opportunities to encounter this disease, and the most important thing is to be aware of the possibility of WD.