A groundbreaking strategy for fabricating YAG:Ce3+ transparent ceramic films via sintering of LRH nanosheets on a sapphire substrate.

Here, we proposed a groundbreaking strategy for fabricating YAG:Ce3+ transparent ceramic films via a novel interface reaction of LRH nanosheets with a sapphire substrate without a tedious process. The incorporation of Gd3+ greatly enhanced the emission intensity of the ceramic film by ∼11.3 times. The prepared transparent ceramic film with a high transmittance of ∼97% is a promising photo-converter for WLEDs.

Circulating microRNA-218 was reduced in cervical cancer and correlated with tumor invasion.

BACKGROUNDS: microRNA-218 was proved to be a tumor-suppressor microRNA in several cancers, but its status in cervical cancer patients has not been established. In this study, we investigated the expression of microRNA-218 in the sera from cervical cancer patients and its relationships with clinico-pathological characteristics. METHODS: The expression of microRNA-218 was detected in the sera of 90 cervical cancer patients and 50 normal age-matched women by quantitative real-time PCR. The clinical data were collected and analyzed by statistical software. RESULTS: In the cancer group, microRNA-218 was reduced significantly in the sera (P < 0.001). Moreover, decreased microRNA-218 was associated with later stages, cervical adenocarcinoma, and lymphatic node metastasis. CONCLUSIONS: microRNA-218 was deregulated in most cervical cancer patients and associated with tumor invasion.