1.
Recent Results Cancer Res
; 63: 77-84, 1978.
Article
in English
| MEDLINE
| ID: mdl-705016
Subject(s)
Antibiotics, Antineoplastic/pharmacology , Animals , Anti-Bacterial Agents/pharmacology , Antibiotics, Antineoplastic/analysis , Bacteria/drug effects , Cells, Cultured , Chromatography, High Pressure Liquid , Chromatography, Paper , Drug Evaluation, Preclinical , Humans , Spectrophotometry, Ultraviolet , Yeasts/drug effects
2.
J Antibiot (Tokyo)
; 30(5): 432-4, 1977 May.
Article
in English
| MEDLINE
| ID: mdl-885802
3.
J Antibiot (Tokyo)
; 26(5): 272-83, 1973 May.
Article
in English
| MEDLINE
| ID: mdl-4360736
Subject(s)
Anti-Bacterial Agents/isolation & purification , Aminoglycosides/analysis , Aminoglycosides/pharmacology , Anti-Bacterial Agents/pharmacology , Bacteria/drug effects , Chemical Phenomena , Chemistry , Fermentation , Hydrolysis , Inositol/analysis , Inositol/pharmacology , Lysine/analysis , Mannose/analysis , Oxidation-Reduction , Periodic Acid
4.
Antimicrob Agents Chemother
; 2(2): 84-8, 1972 Aug.
Article
in English
| MEDLINE
| ID: mdl-4670491
ABSTRACT
Butirosin, a new water-soluble aminoglycosidic antibiotic complex, active against gram-positive and gram-negative bacteria, has been isolated from fermentation filtrates of Bacillus circulans by ion exchange. The complex has been resolved into isomeric A and B components, C(21)H(41)N(5)O(12), by means of Dowex 1 x 1 or Dowex 1 x 2 chromatography. Properties of the free bases and the N, N', N'', N'''-tetraacetyl derivatives of butirosin A and B are given.