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1.
Two commercial test kits for CK-MM isoforms evaluated for early recognition of acute myocardial infarction.
Shah, V D; Yen, S E; Diorio, A F; Hammer, P A.
Clin Chem ; 35(3): 493-4, 1989 Mar.
Article in English | MEDLINE | ID: mdl-2920421

Subject(s)
Creatine Kinase/blood , Myocardial Infarction/enzymology , Reagent Kits, Diagnostic/standards , Humans , Immunoassay , Isoenzymes
2.
Induction of hepatitis in adult Syrian hamster by H-1 virus.
Henry, C J; Diorio, A F.
Proc Soc Exp Biol Med ; 149(1): 23-8, 1975 May.
Article in English | MEDLINE | ID: mdl-1144433

ABSTRACT

The induction of hepatitis in adult hamster by H-1 virus was documented by demonstrating an increase in serum SGOT and SGPT at 3-9 wk postinoculation. The electrophoresis pattern of LDH isoenzymes showed a marked increase in the liver fraction (fraction 5) indicating liver damage in infected hamsters. The pathology displayed in diseased livers revealed a focal degeneration of hepatic cells although infiltration of white cells was not observed. H-1 virus is apparently capable of producing hepatitis (without symptoms) in adult hamsters as well as cause hepatitis and severe cerebral disease in newborn hamsters.


Subject(s)
Hepatitis, Animal/etiology , Parvoviridae/pathogenicity , Alanine Transaminase/blood , Animals , Aspartate Aminotransferases/blood , Cricetinae , Electrophoresis, Polyacrylamide Gel , Hepatitis, Animal/enzymology , Injections, Intraperitoneal , Isoenzymes , L-Lactate Dehydrogenase/blood , Liver/pathology , Microscopy, Electron , Necrosis , Time Factors
3.
The pathways of thiamine biosynthesis. Some factors controlling synthesis of the pyrimidine moiety by thiamine auxotrophs of Neurospora crassa.
Diorio, A F; Lewin, L M.
J Biol Chem ; 243(15): 3999-4005, 1968 Aug 10.
Article in English | MEDLINE | ID: mdl-4875319

Subject(s)
Neurospora/metabolism , Pyrimidines/biosynthesis , Thiamine/biosynthesis , Chromatography, Paper , Enterobacteriaceae/metabolism , Escherichia coli/metabolism , Iron/pharmacology , Pyrimidines/pharmacology , Thiamine/pharmacology , Thiazoles/pharmacology , Zinc/pharmacology
4.
The pathways of thiamine biosynthesis. Separation, purification, and identification of some precursors of the pyrimidine moiety of thiamine produced by neurospora crassa auxotrophs.
Diorio, A F; Lewin, L M.
J Biol Chem ; 243(15): 4006-12, 1968 Aug 10.
Article in English | MEDLINE | ID: mdl-5666944

Subject(s)
Pyrimidines/analysis , Carbon Isotopes , Chromatography , Chromatography, Paper , Electrophoresis , Enterobacteriaceae/metabolism , Formates/metabolism , Spectrophotometry , Thiamine/biosynthesis
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