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1.
Sci Rep ; 12(1): 6678, 2022 04 23.
Article in English | MEDLINE | ID: mdl-35461368

ABSTRACT

Lumbar foraminal stenosis may be caused by osseous and soft tissue structures. Thus, both computed tomography (CT) and magnetic resonance imaging (MRI) play a role in the diagnostic algorithm. Recently, dual-energy CT (DECT) has been introduced for the detection of spinal disorders. Our study's aim was to investigate the diagnostic accuracy of collagen-sensitive maps derived from DECT in detecting lumbar foraminal stenosis compared with standard CT and MRI. We retrospectively reviewed CT, DECT, and MRI datasets in patients with vertebral fractures between January 2015 and February 2017. Images were scored for presence and type of lumbar neuroforaminal stenosis. Contingency tables were calculated to determine diagnostic accuracy and interrater agreement was evaluated. 612 neuroforamina in 51 patients were included. Intraclass correlation coefficients for interrater reliability in detecting foraminal stenoses were 0.778 (95%-CI 0.643-0.851) for DECT, 0.769 (95%-CI 0.650-0.839) for CT, and 0.820 (95%-CI 0.673-0.888) for MRI. Both DECT and conventional CT showed good diagnostic accuracy in detecting lumbar foraminal stenosis but low sensitivities in detecting discoid stenosis. Thus, even though previous studies suggest that DECT has high diagnostic accuracy in assessing lumbar disc pathologies, we show that DECT does not provide additional information for detecting discoid stenosis compared with conventional CT.


Subject(s)
Magnetic Resonance Imaging , Tomography, X-Ray Computed , Constriction, Pathologic/diagnostic imaging , Humans , Magnetic Resonance Imaging/methods , Reproducibility of Results , Retrospective Studies , Sensitivity and Specificity , Tomography, X-Ray Computed/methods
2.
Skeletal Radiol ; 50(7): 1359-1367, 2021 Jul.
Article in English | MEDLINE | ID: mdl-33277674

ABSTRACT

OBJECTIVES: To investigate the diagnostic accuracy of collagen-sensitive maps derived from dual-energy computed tomography (DECT) for the detection of lumbar disk pathologies in a feasibility setting. MATERIALS AND METHODS: We retrospectively reviewed magnetic resonance imaging (MRI), computed tomography (CT), and DECT datasets acquired in patients who underwent periradicular therapy of the lumbar spine from June to December 2019. Three readers scored DECT collagen maps, conventional CT, and MRI for presence, type, and extent of disk pathology. Contingency table analyses were performed to determine diagnostic accuracy using MRI as standard of reference. Interrater agreement within and between imaging modalities was evaluated by computing intraclass correlation coefficients (ICCs) and Cohen's kappa. Correlation between sum scores of anteroposterior disk displacement was determined by calculation of a paired t test. RESULTS: In 21 disks in 13 patients, DECT had a sensitivity of 0.87 (0.60-0.98) and specificity of 1.00 (0.54-1.00) for the detection of disk pathology. Intermodality agreement for anteroposterior disk displacement was excellent for DECT (ICC 0.963 [0.909-0.985]) and superior to CT (ICC 0.876 [0.691-0.95]). For anteroposterior disk displacement, DECT also showed greater within-modality interrater agreement (ICC 0.820 [0.666-0.916]) compared with CT (ICC 0.624 [0.39-0.808]). CONCLUSION: Our data suggest that collagen-sensitive imaging has an added benefit, allowing more accurate evaluation of the extent of disk displacement with higher interrater reliability. Thus, DECT could provide useful diagnostic information in patients undergoing CT for other indications or with contraindications to MRI.


Subject(s)
Lumbar Vertebrae , Tomography, X-Ray Computed , Collagen , Humans , Lumbar Vertebrae/diagnostic imaging , Magnetic Resonance Imaging , Reproducibility of Results , Retrospective Studies , Sensitivity and Specificity
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