ABSTRACT
The paper is concerned with analysis of the survival of 385 lung cancer patients with roentgenologically measured nodular tumor type, verified diagnosis. The patients were followed up for 5-6 years. The effect of tumor growth rates on the survival rates was shown to be the result of the use of various therapeutic methods or their absence. The results suggest that by tumor growth rates, assessed before treatment, one can predict, in most cases, a tumor response to one or another therapeutic method. On the basis of these results an adequate method can be chosen for each individual case.
Subject(s)
Adenocarcinoma/therapy , Carcinoma, Non-Small-Cell Lung/therapy , Carcinoma, Small Cell/therapy , Carcinoma, Squamous Cell/therapy , Lung Neoplasms/therapy , Patient Care Planning/methods , Adenocarcinoma/mortality , Adenocarcinoma/physiopathology , Adult , Aged , Carcinoma, Non-Small-Cell Lung/mortality , Carcinoma, Non-Small-Cell Lung/physiopathology , Carcinoma, Small Cell/mortality , Carcinoma, Small Cell/physiopathology , Carcinoma, Squamous Cell/mortality , Carcinoma, Squamous Cell/physiopathology , Combined Modality Therapy , Female , Humans , Lung Neoplasms/mortality , Lung Neoplasms/physiopathology , Male , Middle Aged , Treatment RefusalABSTRACT
The authors made a retrospective comparative analysis of the results of treatment of 336 lung cancer patients using surgical, radiation and drug techniques taking into account the rate of tumor growth. Differences were observed both in the frequency and terms of survival rates in surgical treatment and markedness of regressive changes in conservative methods of treatment.
Subject(s)
Lung Neoplasms/therapy , Aged , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Cyclophosphamide/administration & dosage , Doxorubicin/administration & dosage , Female , Humans , Lung Neoplasms/pathology , Male , Middle Aged , Pneumonectomy , Prospidium/administration & dosage , Radioisotope Teletherapy , Retrospective Studies , ThoracotomySubject(s)
Adenocarcinoma/diagnostic imaging , Carcinoma, Small Cell/diagnostic imaging , Carcinoma, Squamous Cell/diagnostic imaging , Lung Neoplasms/diagnostic imaging , Adenocarcinoma/pathology , Carcinoma, Small Cell/pathology , Carcinoma, Squamous Cell/pathology , Female , Humans , Lung/diagnostic imaging , Lung/pathology , Lung Neoplasms/pathology , Male , Radiography , Time FactorsABSTRACT
The paper is concerned with the results of radiotherapy of inoperable lung cancer patients. The efficacy of dynamic and conventional fractionation regimens was evaluated in relation to the tumor growth rate and size. The tumor growth rate was shown to be of importance for a local radiation effect: the higher growth rate was, the more pronounced tumor lesion and resorption were. A close relationship between the regression intensity and patients' survival was shown.
