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Rev Pneumol Clin ; 65(3): 137-42, 2009 Jun.
Article in French | MEDLINE | ID: mdl-19524801

ABSTRACT

INTRODUCTION: Community-acquired pneumonia (CAP) is the second leading cause of hospitalization in the respirology department in Abidjan after tuberculosis. Frequently associated with HIV infection, it has a high mortality rate of about 20% to 30%. The aim of this study is to identify the specificities and severity factors associated with bacterial CAP (BCAP) outcome in HIV-positive patients. METHODS: The authors conducted a prospective and comparative preliminary study on two groups of patients: 29 HIV-positive patients with BCAP and 21 HIV-negative patients with BCAP. All of the patients were hospitalized for BCAP with symptoms of severity according to the usual score of severity. RESULTS: The sociodemographic, clinical and paraclinical characteristics were similar in both groups. Failures and deaths were more frequent in the group with HIV infection. In particular, HIV infected patients with a body mass index under 18.5 and a rate of T CD4 lymphocytes lower than 200/mm(3) presented the least favourable evolution. CONCLUSIONS: A more extensive study should help define the appropriate severity criteria for BCAP associated with HIV infection.


Subject(s)
AIDS-Related Opportunistic Infections/mortality , HIV Infections/mortality , Pneumonia/mortality , AIDS-Related Opportunistic Infections/drug therapy , Adult , Anti-Bacterial Agents/therapeutic use , Body Mass Index , CD4 Lymphocyte Count , Community-Acquired Infections/drug therapy , Community-Acquired Infections/mortality , Female , Humans , Male , Pneumonia/drug therapy , Prospective Studies , Severity of Illness Index
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