ABSTRACT
The paper is aimed at illustrating the importance of nonspecific and specific bronchoprovokative tests for diagnosing allergic bronchial asthma by pathophysiologic mechanisms of hyperiritability of airways and making of specific "schok tissue". Besides we tried to explain these exeptional cases which we encounter in our practise, where patients, in spite of absence of any complaints related to breathing, normal physical, findings and normal ventilation function tests, have positive specific or nonspecific bronchoprovocative tests. Evaluation of these condition, as a specific stage in development of allergic bronchial asthma, we concluded that nonspecific and specific bronchoprovokative tests is also important for evaluation of possible occurence of this disease as well as deciding on its prevention.
Subject(s)
Asthma/diagnosis , Bronchial Provocation Tests , Asthma/immunology , Bronchial Hyperreactivity , HumansABSTRACT
Having in mind importance of early detection of the disease, in it phase of development, we have reported a case with seasonal allergic rhinitis and allergic reaction of the lower airways in absence of allergic inflammation and clinically evident bronchial asthma.
Subject(s)
Allergens , Asthma/diagnosis , Pollen , Rhinitis, Allergic, Seasonal/diagnosis , Adult , Humans , Male , Rhinitis, Allergic, Seasonal/physiopathologyABSTRACT
Reporting two of our cases we wanted to point to a great dilemma related to the final diagnosis. Recently, such cases have been more frewuently seen, since in all patients with allergic rhinitis conditions of the lower airways is examined before the administration of the specific immunotherapy. Therefore, we may see patients who are still free of pulmonary sings, despite of positive specific and/or non specific bronchoprovocative tests. The presented cases with evidenced allergic rhinitis are probably in the phase of development of allergic bronchial asthma, the phase of "allergic inflammation" of the lower airways, not clinically manifested yet.
