[Clinico-immunological characteristics of people who worked within the 30-kilometer zone of the accident at the Chernobyl Atomic Power Plant 4 years after the accident]. / Kliniko-immunologicheskaia kharakteristika kontingenta lits, rabotavshikh v 30-kilometrovoi zone avarii na Chernobyl'skoi AES cherez 4 goda posle radiatsionnoi avarii.

Clinical examination with immune status assessment of more than 300 healthy persons, who worked in 30-km Chernobyl NPP zone four years after the accident was carried out. The clinical characters of immune deficiency were detected in 6.67% of examined persons and appeared as repeated respiratory diseases. Significant increase in mean level of leukocytes and lymphocytes was revealed. Activation of T-helper link of cell immunity was determined by increase of CD4+ cells in 35.2% of examined persons, that were lower than in people who took part in Chernobyl accident amelioration in 1986. Decrease in content of T-cells and B-cells was observed in 1/4 and 3/4 of persons correspondingly by rosette assays. No changes in serum immunoglobulins level was observed.

[Metabolism of thiamine and its di- and triphosphorus esters in the blood of patients with neurological symptoms of osteochondrosis]. / Metabolizm tiamina, ego di- i tri-fosfornogo éfirov v krovi bol'nykh s nevrologicheskimi proiavleniiami osteokhondroza.

Concentrations of phosphate esters in blood of patients with vertebral osteochondrosis and activities of enzymes involved in thiamine metabolism have been investigated. The pathological processes were characterized by a decrease in content of thiamine triphosphate while concentration of coenzyme, thiamine diphosphate, was relatively constant. The enzymes involved in the initial and final steps of biosynthesis and degradation of thiamine phosphorylated derivatives play the main role in maintaining vitamin B1 metabolic homeostasis.