ABSTRACT
Herein, we report an intramolecular endo-selective Heck reaction of iodomethylsilyl ethers of phenols and alkenols. The reaction leads to the formation of seven- and eight-membered siloxycycles in excellent yields, which could be further converted into the corresponding allylic alcohols upon oxidation. Thus, this method could be used for the selective (Z)-hydroxymethylation of o-hydroxystyrenes and alkenols. Rapid scan EPR experiments and DFT calculations suggest a concerted ß-hydrogen elimination event to take place in the triplet state.
ABSTRACT
PURPOSES: This cross-sectional study assessed the quality of life and related factors of Vietnamese women during perimenopause in terms of vasomotor, psychosocial, physical, and sexual aspects. MATERIALS AND METHODS: A cross-sectional study on 400 middle-aged women was conducted in Hung Yen, a delta province in Vietnam. Data about socioeconomic characteristics, daily activity patterns, quality of life in terms of vasomotor, psychosocial, physical, and sexual aspects, and level of social support were collected. Tobit multivariate regression model was used to identify factors related to the quality of life among participants. RESULTS: The symptoms of perimenopause appeared to worsen with the increase of age and the existence of such health issues as migraine and diabetes. Meanwhile, exercises, recreational activities, and social support appeared to alleviate the negative impact of perimenopausal symptoms on women. CONCLUSIONS: It is important to address the care needs of women during perimenopausal age, especially their sexual well-being, and development of specific healthcare services and programs focusing on sport, entertainment, and support for women in perimenopause should be facilitated.
Subject(s)
Perimenopause , Quality of Life , Cross-Sectional Studies , Exercise , Female , Humans , Middle Aged , Perimenopause/psychology , Quality of Life/psychology , Social Support , Surveys and QuestionnairesABSTRACT
Introduction: The purpose of this study is to identify the health status and healthcare utilization factors associated with middle-aged women in the rapid urbanization context of Vietnam. Methods: A cross-sectional study with a systematic random sampling technique was conducted in Hung Yen city. A systematic random sampling technique was used to select a sample size of 362 middle-aged women. The collected data included socioeconomic characteristics, health issues, health service utilization, and social support for women in both urban and rural areas. Multivariate regression models were used to determine factors associated with health service utilization and the number of inpatient/outpatient visits. Results: Among 362 participants, the main chronic diseases were diabetes (12.8%), cardiovascular diseases (11.3%), and migraines (9.5%). The proportion of using inpatient and outpatient services among middle-aged women was relatively high (35.8 and 61%, respectively). Women having more support from family and friends were less likely to seek healthcare. Living in rural areas significantly increased the number of inpatient treatments. Regarding health service utilization, the percentage of people using outpatient treatment services accounted for 61.0%, while using inpatient treatment services was reported as 35.8%. The average number of outpatient and inpatient visits per participant were 1.3 and 0.9, respectively. Conclusion: This study revealed a relatively high rate of using healthcare services among women at midlife in a rapidly industrializing city in Vietnam. Screening programs should be implemented for early detection and treatment of chronic diseases in middle-aged women, especially for diabetes. Communication strategies should be adapted to raise awareness of rural women about regular health checkups, and counseling services of healthcare providers should be strongly reinforced. Lifestyle interventions and health promotion programs involving social support should be implemented to improve wellbeing and healthcare-seeking behaviors among middle-aged women.
