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Antibiot Med Biotekhnol ; 32(12): 894-8, 1987 Dec.
Article in Russian | MEDLINE | ID: mdl-3501939

ABSTRACT

Modified cellulose films are recommended to be used as carriers in preparing enzymatic membranes for penicillin-selective electrodes. The results of laboratory testing of the enzymatic penicillin-selective electrode based on the cellulose membrane with immobilized penicillinase are presented. In principle it was shown possible to use the enzymatic electrode in determining penicillin concentration in solutions. Dependence of the electrode reading on the buffer capacity was revealed. Optimal characteristics of the enzymatic membranes and the life-expectancy of the enzymatic electrode were determined.


Subject(s)
Cellulose/analogs & derivatives , Electrodes , Enzymes, Immobilized/pharmacology , Membranes, Artificial , Penicillinase/pharmacology , Penicillins/analysis , Buffers , Catalysis , Cellulose/pharmacology , Dose-Response Relationship, Drug , Equipment Design , Hydrogen-Ion Concentration , Solutions
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