1.
ACS Macro Lett
; 6(9): 903-907, 2017 Sep 19.
Article
in English
| MEDLINE
| ID: mdl-35650888
ABSTRACT
Methods to analyze and compare biomacromolecular surfaces are still in their relative infancy on account of the challenges involved in comparing surfaces computationally. We describe a systems chemistry approach that utilizes polymer-scaffolded dynamic combinatorial libraries to experimentally probe biomacromolecular surfaces in aqueous solution which provides feedback as to the nature of the surfaces, allowing the comparison of three globular proteins and a nucleic acid.