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1.
Khirurgiia (Sofiia) ; (4): 10-3, 2007.
Article in Bulgarian | MEDLINE | ID: mdl-18443528

ABSTRACT

AIM: Lymphomas of the gastrointestinal tract are the most common type of primary extranodal lymphomas, accounting for 5 to 10% of all non-Hodgkin's lymphomas (NHL). PATIENTS AND METHODS: From January 1996 to November 2005, 10 patients with primary intestinal lymphomas were submitted with clinical signs of acute abdomen to the Pediatric surgical department in Sofia. The children presented with radiologically proven intussusception, ileal obstruction or peritonitis due to bowel perforation. RESULTS: At exploration the tumor was located in the ileum in 4 cases, in the terminal ileum and coecum in 3 cases, appendix in one and multiple sites were found in 2 cases. Children with localized disease underwent radical resection of the tumor mass with ileo - transverso anastomosis (3), partial bowel resection (4), and appendectomy (1) whereas in 2 children with advanced disease diagnostic biopsy alone with temporary ileostomy in one were accomplished. According to histology, 5 patients had Burkitt lymphoma and 5 lymphoblast NHL. The children were treated according CHOP. Over five - years relapse - free survival for localized disease accounts 6 children. CONCLUSION: Primary NHL in children often presents with acute abdominal condition requiring surgical exploration. Prognosis depends of adequacy of surgical resection and the adjuvant chemotherapy.


Subject(s)
Abdomen, Acute/etiology , Intestinal Neoplasms , Lymphoma, Non-Hodgkin , Abdomen, Acute/diagnosis , Abdomen, Acute/surgery , Child , Disease-Free Survival , Female , Humans , Intestinal Neoplasms/complications , Intestinal Neoplasms/diagnosis , Intestinal Neoplasms/surgery , Lymphoma, Non-Hodgkin/complications , Lymphoma, Non-Hodgkin/diagnosis , Lymphoma, Non-Hodgkin/surgery , Male
2.
Khirurgiia (Sofiia) ; 49(3): 18-23, 1996.
Article in Bulgarian | MEDLINE | ID: mdl-9011666

ABSTRACT

This is a retrospective analysis of 651 children, aged 0 to 14 years, presenting chest and abdominal injuries, treated over a 6-year period in the section of pediatric surgery of the Emergency Medicine Institute "Pirogov". The results of studies on the etiopathogenesis of chest and abdominal trauma, patterns of associated lesions and quality of prehospital aid are discussed. Experience with the application of updated noninvasive and invasive methods of diagnosis, as well as the scope of surgical approach to the variety of lesions by resorting to organ sparing and organ salvaging operative procedures are analyzed. On the basis of observations and experience gained to date, the indications for application of the prospective method of nonoperative treatment of certain organic lesions in the practice of pediatric surgery are broadened. The overall research project provides good reason to work out an algorithm of the therapeutic approach to children presenting abdominal and chest trauma.


Subject(s)
Abdominal Injuries/epidemiology , Multiple Trauma/epidemiology , Thoracic Injuries/epidemiology , Abdominal Injuries/diagnosis , Abdominal Injuries/surgery , Adolescent , Age Distribution , Bulgaria/epidemiology , Child , Female , Humans , Male , Multiple Trauma/diagnosis , Multiple Trauma/surgery , Retrospective Studies , Sex Distribution , Thoracic Injuries/diagnosis , Thoracic Injuries/surgery
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