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Spec Care Dentist ; 21(2): 60-2, 2001.
Article in English | MEDLINE | ID: mdl-11484582

ABSTRACT

A case history of a woman with gingival overgrowth (GO) induced by amlodipine is presented. A 49-year-old Japanese woman, who was taking amlodipine, had gingival overgrowth and swelling on examination. No specific periodontal treatment was provided to the patient for the GO; however, the amlodipine was replaced with an ACE inhibitor after consultation with her medical practitioner. Within two months, the suspension of amlodipine resulted in a significant improvement in her periodontal condition. Failure to control the hypertension caused the physician to re-prescribe amlodipine. After three months, the gingival overgrowth returned; however, its severity was less when compared with the original periodontal condition, due to reduction in drug dose and periodontal therapy. This experience suggests that temporary suspension of a drug which can induce GO can improve the periodontal condition without the aid of surgical treatment.


Subject(s)
Amlodipine/adverse effects , Antihypertensive Agents/adverse effects , Calcium Channel Blockers/adverse effects , Gingival Overgrowth/chemically induced , Adrenergic beta-Antagonists/therapeutic use , Amlodipine/administration & dosage , Angiotensin-Converting Enzyme Inhibitors/therapeutic use , Antihypertensive Agents/administration & dosage , Antihypertensive Agents/therapeutic use , Calcium Channel Blockers/administration & dosage , Female , Gingival Hemorrhage/chemically induced , Gingival Hemorrhage/prevention & control , Gingival Overgrowth/prevention & control , Gingival Pocket/chemically induced , Gingival Pocket/prevention & control , Humans , Middle Aged , Recurrence
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