ABSTRACT
Subclinical hypothyroidism is a rather common disorder of the thyroid gland. Despite the fact that subclinical hypothyroidism has no clear-cut clinical picture, this condition is associated with changes in various organs and systems, moreover, it is a risk factor of cardiovascular diseases. The article summarizes the available data on subclinical hypothyroidism, principles of its diagnostics and treatment.
Subject(s)
Cardiovascular Diseases , Hormone Replacement Therapy/methods , Hypothyroidism , Thyroxine , Asymptomatic Diseases , Cardiovascular Diseases/epidemiology , Cardiovascular Diseases/prevention & control , Humans , Hypothyroidism/diagnosis , Hypothyroidism/epidemiology , Hypothyroidism/physiopathology , Hypothyroidism/therapy , Patient Selection , Risk Factors , Thyroxine/analysis , Thyroxine/pharmacologyABSTRACT
The article presents data on the relationship between thyroid dysfunction and cardiovascular diseases. The role of dyslipidemia, adipokines (adiponectin, leptin, resistin), C-reactive protein, deficiency of vitamin D3 in the development of cardiovascular disease in hypothyroidism is discussed. The article describes characteristics of myocardial remodeling, its dysfunction and their correlation with risk factors of cardiovascular diseases in patients with hypothyroidism.
