[Mitotic activity of epithelium in crypts of rats' empty intestine and tissue basophils in the event of intestinal syndrome of radiation disease treated with poly-radio-modification]. / Mitoticheskaia aktivnost' épiteliia kript toshchei kishki krys i tkanevye bazofily pri kishechnom sindrome luchevoi bolezni v usloviiakh poliradiomodifikatsii.

In the experiment with white mongrel puberal male rats, morphological and statistical methods were used to study mitotic activity (MA) in the crypt epithelium in the empty intestine and morphofunctional state of tissue basophils (TB) in the intercrypt stroma after a single gamma-irradiation at the dose of 10 Gy and polyradiomodification including exposure to EMR in the UHF range (2.4 GHz, 10 mW/cm2, 2.5 min), normobaric oxygen (NO) or hypoxic gaseous mixture (HGM) containing 8% of O2 and 92% of N2. Polyradiomodification with the use of EMR and HGM or NO was found to be more effective as compared with the use of each of these radioprotective methods separately. A combination of EMR + HGM + II gave more apparent and earlier effect of MA recovery and TB activation as compared to EMR + NO + II.

[Morpho-functional status of large-cell hypothalamic nuclei following chronic exposure to wide-range electromagnetic impulses]. / Morfofunktsional'noe sostoianie krupnokletochnykh iader gipotalamusa pri khronicheskom vozdeistvii shirokopolosnykh élektromagnitnykh impul'sov.

In a experiment with white nubilous male rats the morphofuntional state of secretory neurons (SN) of the large-cell hypothalamic nuclei (LCHN) was evaluated with the morphological, morphometric and statistical methods following electromagnetic exposure (500, 100 and 50 impulses once a week) inducing in the animal body the averaged current densities of 1.5 kA/m2. It was stated that 100 EMI a week called forth opposite LCHN reactions, that is suppression of synthesis and elimination of SN neuro-secret in supraoptic nuclei and their activation in the paraventricular nuclei. LCHN reaction to the other frequencies of EM impulses was uniform and included rearrangement of both neurosecretory centers for a lower functional activity. Decrease in the number of effectively functioning SN due to the EM exposure may point to a dead-aptive effect of this factor.

[Morphological reactivity of neurons following chronic exposure to wide-range electromagnetic impulses]. / Morfologicheskaia reaktivnost' neironov pri khronicheskom deistvii shirokopolosnykh élektromagnitnykh impul'sov.

In an experiment with white nubilous male rats the morphofunctional state of neurons in the cerebral hemisphere cortex was evaluated with the morphological and statistical methods following electromagnetic exposure (500 impulses once a week for 5, 7 and 10 mos.) inducing in the animal body the averaged current densities of 0.21 and 1.5 kA/m2. Chronic exposure to electromagnetic fields with the density of 0.21 kA/m2 was found to increase the biosynthetic activity of neurons by way of compensation and adaptation and level at the end of experiment, whereas the density of 1.5 kA/m2 brings about profound structural and functional disorders in and inhibits the biosynthetic activity of the neurons.

[The therapeutic efficacy of sodium nucleinate and monoribonucleotides based on keratoconjunctival test data]. / Lechebnaia éffektivnost' nukleinata natriia i monoribonukleotidov po dannym keratokon''iunktival'noi proby.

The possibility of using sodium nucleinate for the treatment of acute dysentery has been confirmed in experiments on guinea pigs with the use of the keratoconjunctival test as an experimental model. The capacity of sodium nucleinate to enhance the antibiotic sensitivity of shigellae isolated from infected eyes to kanamycin, tetracycline and chloramphenicol has been established. The effect produced by individual ribonucleotides contained in sodium nucleinate have been studied and found to be differently directed.