ABSTRACT
AIM: Evaluate the real-life experience with ocriplasmin on vitreomacular traction (VMT) release and full-thickness macular hole (FTMH) closure in Portugal. METHODS: Multicentric, retrospective study of 83 eyes of 78 patients who were treated with intravitreal ocriplasmin for VMT with and without FTMH. Primary outcomes were VMT release and FTMH closure. Secondary outcomes included visual acuity changes and structural features on spectral-domain ocular coherence tomography. RESULTS: VMT resolved in 47 of the 83 eyes (56.6%) and 6 of the 12 FTMH were closed (50.0%). Mean best-corrected visual acuity (BCVA) improved from 65.1 at baseline to 70.8 ETDRS letters at the end of follow-up (p < 0.0001) with a mean follow-up of 138.8 days. Improvement in BCVA was significantly better in eyes with VMT release (p = 0.021). Approximately 73% of patients had normal ellipsoid zone integrity at the end of follow-up, 87% had no neurosensorial detachment and 40% had no intra- or subretinal fluid. CONCLUSION: VMT release and FTMH closure were achieved in more than half of the treated eyes and were correlated with significant BCVA improvements and favorable baseline characteristics. In fact, if a careful patient selection is carried out, VMT resolution with ocriplasmin can be optimized, tailoring the best approach to each patient.
Subject(s)
Fibrinolysin/administration & dosage , Peptide Fragments/administration & dosage , Tomography, Optical Coherence/methods , Vitreous Detachment/drug therapy , Aged , Female , Follow-Up Studies , Humans , Intravitreal Injections , Male , Retrospective Studies , Time Factors , Treatment Outcome , Visual Acuity , Vitreous Detachment/diagnosis , Vitreous Detachment/physiopathologyABSTRACT
We describe the cupid fixation technique, which allows safe repositioning of a subluxated intraocular lens (IOL). Under subconjunctival anesthesia, the body of the subluxated IOL is perforated with a 10-0 polypropylene suture on a straight needle. The IOL is then centered and fixated at the sclera overlying the ciliary sulcus; the knot is tied beneath a previously created limbal intrascleral pocket. No intraoperative complications occurred in 24 cases in which the technique was performed, and successful IOL centration was achieved.
Subject(s)
Artificial Lens Implant Migration/surgery , Lens Implantation, Intraocular/methods , Suture Techniques , Anesthesia, Local/methods , Humans , Intraoperative Complications , Polypropylenes , Postoperative Complications , Reoperation , Sutures , Treatment OutcomeABSTRACT
We describe the case of a monocular 72-year-old man who presented with spontaneous acute visual decrease in the left eye 2 years after uneventful phacoemulsification with intraocular lens (IOL) and standard capsular tension ring (CTR) implantation. Dilated fundoscopy revealed aphakia and complete vitreous luxation of the entire capsular bag-IOL-CTR complex.
