Subject(s)
Kidney Neoplasms/pathology , Leiomyoma/pathology , Adult , Biomarkers, Tumor , Biopsy , Carcinoma, Renal Cell/diagnosis , Diagnosis, Differential , Diagnostic Imaging , Female , Humans , Kidney Neoplasms/diagnosis , Kidney Neoplasms/surgery , Leiomyoma/diagnosis , Leiomyoma/surgery , Neoplasms, Second Primary/diagnosis , Neoplasms, Second Primary/pathology , Neoplasms, Second Primary/surgery , Nephrectomy/methods , Uterine Neoplasms/surgerySubject(s)
Humans , Male , Spleen/abnormalities , Testis/abnormalities , Scrotum/abnormalities , Gonads/abnormalitiesABSTRACT
No disponible
No disponible
Subject(s)
Humans , Female , Adult , Leiomyoma/diagnosis , Leiomyoma/surgery , Kidney Neoplasms/diagnosis , Kidney Neoplasms/surgery , Neoplasms, Mesothelial/complications , Neoplasms, Mesothelial/diagnosis , Angiolipoma/complications , Angiolipoma/diagnosis , Leiomyoma/physiopathology , Leiomyoma , Kidney Neoplasms/physiopathology , Kidney Neoplasms , Carcinoma/complications , Carcinoma/diagnosis , Angiolipoma/surgery , AngiolipomaSubject(s)
Carcinosarcoma/pathology , Urinary Bladder Neoplasms/pathology , Female , Humans , Middle AgedABSTRACT
Papillary squamous craniopharyngioma is an unusual variant of craniopharyngioma that presents almost exclusively in adults. We report a case of a 51-year-old man, who presented with visual and mental symptoms. A CT scan showed a suprasellar and intraventricular, uncalcified mass. After craniotomy a partly solid and cystic mass was resected. Light microscopy examination of the solid part shows a well-differentiated papillary squamous epithelium arranged in anastomosing cords and papillae. Peripheral palisading of cells, "stellate reticulum" and keratoid nodules were not present. No cholesterol clefts or calcifications are seen. The differential diagnosis of this tumor is discussed.
Subject(s)
Craniopharyngioma/diagnosis , Pituitary Neoplasms/diagnosis , Diagnosis, Differential , Humans , Male , Middle Aged , Tomography, X-Ray ComputedABSTRACT
We report the first case of Epstein Barr virus (EBV) positive non-Hodgkin's lymphoma occurring 20 years after continuous phenytoin therapy for idiopathic epilepsy. This malignant lymphoproliferative disease was preceded by an phenytoin-associated benign reactive lymphadenopathy. Serological findings suggested a chronic active EBV infection. Immunohistochemistry showed that neoplastic cells expressed B antigens (CD20, lambda) and the bcl-2 protein. The presence of EBV-encoded latent membrane protein 1 (LMP 1) was also expressed on neoplastic cells. Cytotoxic chemotherapy (CHOP) reversed the non-Hodgkin's lymphoma.
Subject(s)
Anticonvulsants/adverse effects , Antineoplastic Combined Chemotherapy Protocols , Epilepsy/drug therapy , Lymphoma, Non-Hodgkin/virology , Phenytoin/adverse effects , Tumor Virus Infections/complications , Antigens, CD20/metabolism , Antineoplastic Agents/therapeutic use , Cyclophosphamide/therapeutic use , Doxorubicin/therapeutic use , Humans , Immunohistochemistry , Lymphoma, Non-Hodgkin/drug therapy , Male , Middle Aged , Prednisone/therapeutic use , Proto-Oncogene Proteins c-bcl-2/metabolism , Vincristine/therapeutic useABSTRACT
Nowadays incidental focal hepatic lesions are detected rather frequently by abdominal imaging. A 12 cm diameter liver mass was incidentally found in an abdominal ultrasound in a 26 years old man. Despite an extensive diagnostic workup, the diagnosis of hepatocellular carcinoma could only be attained through the histological study of the surgical specimen. Differential diagnosis of a focal hepatic lesion is reviewed. Radiological assessment and biopsy procedures should follow a protocol. Where doubt exists about the presence of malignancy after fulfilling the diagnostic protocol we believe that it is justified to remove the lesion. This policy allowed to treat successfully our patient. Hepatocellular carcinoma in noncirrhotic occurs much less frequently than in cirrhotic liver, and moreover, it is specially rare to find at such a young age a non fibrolamellar hepatocarcinoma non associated with cirrhosis or a chronic viral infection. Diagnosis, treatment and prognosis of hepatocellular carcinoma are reviewed.
Subject(s)
Carcinoma, Hepatocellular/diagnostic imaging , Liver Diseases/diagnosis , Liver Neoplasms/diagnostic imaging , Adult , Carcinoma, Hepatocellular/pathology , Carcinoma, Hepatocellular/surgery , Diagnosis, Differential , Hepatectomy , Hepatic Artery/diagnostic imaging , Humans , Liver/pathology , Liver Neoplasms/pathology , Liver Neoplasms/surgery , Magnetic Resonance Imaging , Male , Tomography, X-Ray Computed , UltrasonographyABSTRACT
We present four cases of endodermal sinus tumor affecting children (median age, 20 months). Three tumors were located in the sacrococcygeal region and one in the right testicle. All cases were diagnosed by fine needle aspiration biopsy. The most characteristic features were cells arranged in a papillary-like configuration, vacuolated cytoplasm and intracellular and extracellular deposits of pink, homogeneous material. Immunocytochemical study showed alpha-fetoprotein-positive cells. Ultrastructural study showed intracytoplasmic inclusions of electron-dense material and basement membrane-like material in the intercellular spaces.
Subject(s)
Mesonephroma/pathology , Sacrococcygeal Region/pathology , Testicular Neoplasms/pathology , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Biopsy, Needle , Bleomycin/administration & dosage , Cisplatin/administration & dosage , Female , Humans , Infant , Male , Mesonephroma/therapy , Mesonephroma/ultrastructure , Testicular Neoplasms/therapy , Testicular Neoplasms/ultrastructure , Testis/pathology , Vinblastine/administration & dosage , alpha-Fetoproteins/analysisABSTRACT
We report a series of 9 leiomyomas of the esophagus treated surgically. We review the literature, emphasizing diagnostic and therapeutic aspects, calling special attention to the good results obtained by submucosal enucleation of the tumor.
