ABSTRACT
Case report of a premature baby girl who presented with a right cervico-facial mass which caused severe respiratory difficulty. The patient underwent subtotal resection of the mass whose pathologic specimen report revealed heterotopic cerebral tissue compatible with encephalocele. A head and neck CT Scan performed could not evidence a connection between the mass and the cranial cavity, reason for which the possibility of encephalocele was disregarded. After subtotal resection of the mass, the tumor began to grow from soft palate and the patient died from respiratory complications at four months of age. Autopsy reported heterotopic cerebral tissue from neck and soft palate; right lung pneumonia and infection by CMV. Although the heterotopic cerebral tissue was reported as benign, the clinical characterization of this mass is compatible with a malignant behavior due to the aggressiveness of its growth.
Subject(s)
Brain , Choristoma/diagnosis , Facial Neoplasms/diagnosis , Head and Neck Neoplasms/diagnosis , Mandible/abnormalities , Choristoma/congenital , Choristoma/pathology , Diagnosis, Differential , Facial Neoplasms/congenital , Facial Neoplasms/pathology , Female , Head and Neck Neoplasms/congenital , Head and Neck Neoplasms/pathology , Humans , Infant, Newborn , Infant, Premature , Mandible/pathologyABSTRACT
Este es el caso de una paciente prematura que presentó una masa faciocervical derecha que le provocó dificultad respiratoria severa. La bebé fue sometida a excisión subtotal de la masa de cuyo tejido se realizó un estudio patológico donde se informó tejido cerebral heterotópico compatible con encefalocele. Por tomografía computadorizada de cabeza no se evidenció conección de la masa con la cavidad craneal, por lo que se descarta encefalocele. Falleció a los 4 meses con dificultad respiratoria. En la autopsia realizada se informó tejido cerebral heterotópico en cuello y paladar; neumonía pulmón derecho e infección por citomegalovirus. El tejido cerebral heterotópico a pesar de que se informa como benigno, en este caso se comportó como maligno por lo agresivo de su crecimiento
Subject(s)
Humans , Female , Infant, Newborn , Cerebrum , Choristoma/diagnosis , Facial Neoplasms/diagnosis , Mandible/abnormalities , Head and Neck Neoplasms/diagnosis , Choristoma/congenital , Choristoma/pathology , Diagnosis, Differential , Facial Neoplasms/congenital , Facial Neoplasms/pathology , Infant, Premature , Mandible/pathology , Head and Neck Neoplasms/congenital , Head and Neck Neoplasms/pathologyABSTRACT
The insulinmic response to an i.v. glucose load was determined in 129 pregnant women, early in the third trimester of pregnancy, with normal I K but with familiar diabetes and in 12 controls, with normal I K and without familiar diabetes. Results show that there is not a significative difference between the groups. In both groups, 30% of patients show a greater insulin release, likely expression of a functional pancreatic overload.
Subject(s)
Insulin/metabolism , Pregnancy in Diabetics/diagnosis , Blood Glucose/analysis , Female , Glucose , Humans , Infusions, Parenteral , Insulin Secretion , Pregnancy , Pregnancy Trimester, ThirdABSTRACT
Serratia marcescens rarely causes infections in newborn infants. We recently studied an epidemic caused by a multiply-resistant, serotype 014:H12 Serratia marcescens that involved 42 infants. Cutaneous abscesses at previous intravenous infusion sites occurred nine times, usually required surgical drainage, and were the most striking infections during the outbreak. Six infants developed Serratia bacteremia and two died with Serratia meningitis; 34 patients were colonized with Serratia but remained uninfected. An epidemiologic investigation of the 83 infants at risk in the nursery assessed factors predisposing them to colonization or infection with the epidemic organism. Colonization of the throat, umbilicus, gastrointestinal tract, or skin was frequent among infants as was carriage of Serratia on nursey employees' hands. Infected and colonized infants were the most important reservoir for Serratia in the nursery and cross-infection between infants readily occurred. Scalp-vein needles appeared to provide a portal of entry of Serratia in colonized infants, predisposing them to abscess formation and bacteremia.
