Impact of an emergency department nursing intervention on continuity of care, self-care, and psychological symptoms.

BACKGROUND: The emergency department plays a crucial role in providing acute care to patients. Nursing interventions in this setting are essential for improving the continuity of care, enhancing patients' self-care abilities, and reducing psychological symp-toms. AIM: To evaluate the effect of nursing interventions in the emergency department on these indicators in an emergency department. METHODS: A retrospective analysis was conducted on 120 patients admitted to the emergency department between January 2022 and May 2023. The patients were divided into two groups: The control group (conventional nursing intervention) and the observation group (conventional nursing intervention + emergency department nursing intervention). The two groups were compared regarding continuity of care, self-care ability, psychological symptoms, and satisfaction with care. RESULTS: The emergency department nursing interventions significantly improved the continuity of care, enhanced patients' self-care abilities, and reduced psychological symptoms such as anxiety and depression. CONCLUSION: Nursing interventions in the emergency department positively impact continuity of care, self-care, and psychological symptoms. However, it is important to acknowledge the limitations of this study, including the small number of studies, variable methodological quality, and the heterogeneity of the study population. Future research should address these limitations and further explore the effects of different types of nursing interventions in the emergency department. Additionally, efforts should be made to enhance the application and evaluation of these interventions in clinical practice.

Serum Salusin-ß Levels Are Correlated with Slow Coronary Flow.

CONTEXT: Slow coronary flow (SCF) is a special coronary microvascular disorder associated with recurrent chest pain. The pathogenesis of SCF remain unclear. OBJECTIVES: We sought to assess whether serum salusin-ß levels are correlated with SCF. METHODS: We enrolled 76 patients with angiographically confirmed SCF and 108 age- and gender-matched controls. We measured serum salusin-ß levels by enzyme-linked immunosorbent assay and coronary flow rate was assessed using thrombolysis in myocardial infarction frame count (TFC). RESULTS: Serum salusin-ß levels were elevated in SCF patients compared with controls (4.33 [range 3.52-5.87] nmol/L vs. 3.76 [range 2.98-4.67] nmol/L). Multivariate logistic regression analysis revealed that salusin-ß in serum was the independent predictor of SCF (odds ratio = 1.814). Serum salusin-ß levels were independently correlated with mean-TFC (r = 0.355, p = 0.002). CONCLUSIONS: Serum salusin-ß levels were independently associated with SCF. Therefore, our findings implicate a potential role of salusin-ß in the pathophysiology of SCF and provide insights on both risk stratification and modification in this patient population.

[Coumarins of Anemone raddeana Regel and their biological activity].

To study the coumarins of Anemone raddeana Regel, the compounds were separated by silica gel column chromatography and HPLC. Their structures were identified by their physicochemical property and spectral analysis. Two new compounds were isolated and identified as 4, 7-dimethoxyl-5-methyl-6-hydroxy coumarin (1) and 4, 7-dimethoxyl-5-formyl-6-hydroxycoumarin (2). The bioassays indicated that compounds 1 and 2 could significantly inhibit the proliferation of cancer cell, and showed the agonist effect on the transactivity of retinoic acid receptor-alpha (RARalpha). In addition, the two compounds had inhibitory effect against human leukocyte elastase (HLE).

Health-related quality of life of liver transplant recipients: a single center experience.

BACKGROUND/AIMS: To evaluate the health related quality of life (HRQOL) of liver transplant recipients and to identify risk factors influencing post-operative HRQOL. METHODOLOGY: Adult patients who underwent primary liver transplantation from 2009 to 2010 were asked to complete a HRQOL survey at pre-operation and one year postoperatively. We compared the HRQOL of liver transplant recipients at pre-transplantation and one year postoperatively to the general population. Pre-transplant variables were analyzed to identify the risk factors influencing postoperative HRQOL. RESULTS: Pre-transplant HRQOL was significantly lower than that of the general population and significantly improved at one year postoperatively. Multivariate analyses suggested hepatocellular carcinoma, pre-transplant hypertension and high model for end-stage liver disease score were independent risk factors for postoperative physical component summary (PCS); and higher education level, marital status and lower income level negatively impacted on the postoperative mental component summary (MCS). CONCLUSIONS: Factors influencing postoperative HRQOL were identified in the present study. Transplant centers should pay more attention to patients with above-mentioned risk factors and strive to improve the HRQOL.

[Perioperative nursing of 50 recipients undergoing adult-to-adult living donor liver transplantation].

OBJECTIVE: To summarize the perioperative nursing experience for recipients undergoing adult-to-adult living donor liver transplantation(A-ALDLT). METHODS: 50 cases of recipients undergoing A-ALDLT in our hospital January 2002 to July 2006 were retrospectively analyzed for perioperative nursing. RESULTS: All the successful operations for A-ALDLT got without nursing complications. 1-year survival rate was 92%, which means the care effect was satisfactory. CONCLUSION: Perioperative nursing is one important factor of elements to guarantee the success of LDLT. The actively and effectively perioperative nursing measures are the important insurance to the recipients' recovery from graft operation.

[Polyethylene glycol-accompanied ion-exchange chromatography to purify recombinant hepatitis B virus surface antigen].

The dissociation of virus-like particles of Hepatitis B surface antigen (HBsAg) during the adsorption-desorption on the solid-phase of chromatography is a main challenge for its purification. Herein, poly (ethylene glycol) (PEG) was applied as an additive during the purification of HBsAg from recombinant Chinese hamster ovary (CHO) cell culture to improve the HBsAg recovery and protect its structural assembly. The presence of 1% of PEG10000 in the mobile phase of ion-exchange chromatography (IEC) of DEAE-Sepharose FF column could increase the recovery of HBsAg from about 55% to 80%, with a similar purification (-fold) (about 12) compared with the absence of PEG. Importantly, glycosylated protein forms of HBsAg were reserved well by PEG-accompanied chromatography. Furthermore, size exclusion chromatography-multiangle laser light scattering (SEC-MALLS) analysis was performed on line to monitor the aggregates, particle size and molecular weight distribution of HBsAg. The results demonstrated that the HBsAg particle size and assembly are more homogenous after adding PEG in the mobile phase of IEC than no PEG added in the mobile phase.