ABSTRACT
OBJECTIVE: To assess the effectiveness of emergency single-dose levonorgestrel contraception in preventing unintended pregnancies among woman who visited the emergency department (ED) due to sexual assault (SA). METHODS: We conducted a retrospective chart review in a university hospital in South Korea. Cases from November 10, 2006 to November 9, 2009 were enrolled. Information from the initial visit to the ED and subsequent follow-up visits to the gynecology outpatient clinic was collected. RESULTS: In total, 1,179 women visited the ED due to SA. Among them, 416 patients had a gynecological examination and 302 patients who received emergency contraception (EC) (1.5 mg single-dose levonorgestrel) at the ED due to SA were enrolled. Ten patients did not return for follow-up examinations. In follow-up visits at the outpatient clinic, two pregnancies were confirmed, which showed the failure rate of the EC to be 0.68%. CONCLUSION: Single-dose levonorgestrel EC is extremely effective at preventing pregnancy among victims of SA.
Subject(s)
Female , Humans , Pregnancy , Ambulatory Care Facilities , Contraception , Contraception, Postcoital , Emergencies , Follow-Up Studies , Gynecological Examination , Gynecology , Levonorgestrel , Republic of Korea , Retrospective StudiesABSTRACT
OBJECTIVES: To evaluate the effects of transdermal estrogen gel on postmenopausal Korean women. METHODS: In this retrospective study, 49 healthy postmenopausal women were treated with transdermal gel (0.1%, 1.5 mg/day +/- progestogen) for 1 year. After 3 months of transdermal hormone therapy (HT), deviations from baseline of the global index for menopausal symptoms and the frequency of side effects were evaluated. Anthropometric factors including weight, body mass index, waist circumference, and metabolic parameters (such as serum cholesterol, lipoprotein(a), fasting glucose, fibrinogen, C-reactive protein, and deoxypyridinoline levels) were measured at baseline and after three, six, and twelve months of HT. In addition, bone mineral density was also measured at the lumbar spine and femoral neck at baseline and after six and twelve months of HT. Differences between baseline values and subsequent post-HT measurements were compared. RESULTS: After 3 months of transdermal HT, the global index for menopausal symptoms decreased significantly (P < 0.001). Side effects within 3 months included problems related to the breast, which were most common (32.1%), followed by headache (17.8%) and skin irritation (14.3%). Anthropometric factors did not change after HT, however, metabolic parameters creased significantly. There was a notable increase in bone mineral density at the lumbar spinebut not at the femoral neck. CONCLUSION: Transdermal gel HT improves menopausal symptoms and metabolic parameters in postmenopausal Korean women and increases bone mineral density at the lumbar spine.
Subject(s)
Female , Humans , Amino Acids , Body Weight , Bone Density , Breast , C-Reactive Protein , Cholesterol , Estrogens , Fasting , Femur Neck , Fibrinogen , Glucose , Headache , Hormone Replacement Therapy , Lipoprotein(a) , Menopause , Retrospective Studies , Skin , Spine , Waist CircumferenceABSTRACT
OBJECTIVE: To compare laparoscopic surgery with conventional abdominal surgery in patients with early stage endometrial cancer. METHODS: A retrospective review of 63 patients with early stage endometrial cancer managed between March 2003 and May 2005. Two groups were defined whether they had been treated by laparoscopy (case group: n=26) or by laparotomy (control group: n=37). We compared age, body mass index (BMI), hemoglobin change, operation time, number of pelvic lymph nodes, hospital stay, case with adjuvant treatment and recurrence between two groups. RESULTS: There was no statistical difference in characteristics (age, BMI, nulliparity, previous abdominal surgery, FIGO stage, histologic grade). between case and control group. In addition, there was no statistical difference in operation data and outcomes between two groups. Hemoglobin changes were 1.1 g/dL (case group) vs 1.7 g/dL (control group) (p=0.072). Operation time was 131 min vs. 115 min. The numbers of lymph nodes obtained were 8.7 vs 7.7 (right) 9.2 vs. 7.6 (left). Hospital stays were 8.4 vs. 9.2 days. Adjuvant treatment cases were 7 vs. 15. Recurrent case was one in each group. Two patients initially evaluated by laparoscopy were converted to laparotomy due to bleeding and adhesion. CONCLUSION: Laparoscopic surgery for treatment of early endometrial cancer is a safe and effective alternative to laparotomy . However, long-term survival and risk of recurrence have yet to be determined.
Subject(s)
Female , Humans , Body Mass Index , Endometrial Neoplasms , Hemorrhage , Hysterectomy , Hysterectomy, Vaginal , Laparoscopy , Laparotomy , Length of Stay , Lymph Nodes , Parity , Recurrence , Retrospective StudiesABSTRACT
OBJECTIVE: To investigate the perinatal and clinical characteristics of cerebral palsy (CP) following preterm or term birth. METHODS: A total of 75 infants born and diagnosed as CP in our hospital from October 1994 to December 2004 were recruited retrospectively. Their maternal and perinatal outcomes and the type, involved lesion and severity of CP were analyzed. RESULTS: The incidence of CP was 0.23%, which showed decreasing pattern according to advancing gestational age at birth. CP was more frequent (6.7-times) in multifetal pregnancy. Male to female ratio was 1.5: 1. After excluding five infants with major congenital anomalies, 55 (79%) infants were born before 37 weeks' gestation (preterm CP) and 15 (21%) infants were born beyond 37 weeks' gestation (term CP). Eighty-six percent of preterm CP had significant neonatal morbidities, but only 6 out of 15 infants in term CP had significant perinatal events including hypoxic ischemic encephalopathy, meconium aspiration syndrome, and seizure of unknown origin. The most common type of preterm CP was spastic (95%), whereas the types of term CP were more diverse; spastic in 67%, athetoid in 20%, dystonic in 7%, and hypotonic in 7%. Regarding the involved lesions, the most common type was diplegic in preterm CP and quadriplegic in term CP. CONCLUSION: In contrast to preterm CP, term CP had significantly less perinatal risk factors, and their type and involved lesion showed more diverse patterns. These findings may implicate that more heterogenous etiologies are involved in pathogenesis of term CP.
Subject(s)
Female , Humans , Infant , Infant, Newborn , Male , Pregnancy , Cerebral Palsy , Gestational Age , Hypoxia-Ischemia, Brain , Incidence , Meconium Aspiration Syndrome , Muscle Spasticity , Parturition , Premature Birth , Retrospective Studies , Risk Factors , Seizures , Term BirthABSTRACT
OBJECTIVE: The aim of this study was to compare peri-operative morbidity and safety of patients treated by laparoscopically-assisted radical vaginal hysterectomy (LARVH)with laparoscopic pelvic lymphadenectomy (LPL)and radical abdominal hysterectomy (RAH)with pelvic lymph node dissection (PLND) in early stage of cervical cancer. METHODS: Since September 2004,all patients with FIGO stage Ia-IIa cervical cancer undergoing radical surgery by members of our division have been entered into a prospective database. Two surgeons at our center have performed LARVH by Schneider method on all surgically appropriate patients. RESULTS: Between September 2004 and May 2005, 26 patients were performed LARVH with LPL,30 patients were performed RAH with PLND. There were no differences in estimated blood loss, the number of lymph nodes, duration of hospital stay and postoperative complications.But operative time was significantly prolonged in LARVH group. Intraoperative complications in the LARVH with LPL group included: bladder injuries(2), shift to laparotomy due to ureter injury(1). There was one case of vesicovaginal fistula in the RAH group. CONCLUSION: LARVH with LPL in early stage of cervical cancer is a safe and technically effective alternative to RAH. Despite the inherent limitations of LARVH with LPL and its associated learning curve, the procedure conveys many advantages over the open laparotomy technics in terms of postoperative wound pain and recovery. However further study is needed to evaluate long-term recurrence rate and survival rate.
Subject(s)
Female , Humans , Hysterectomy , Hysterectomy, Vaginal , Intraoperative Complications , Laparotomy , Learning Curve , Length of Stay , Lymph Node Excision , Lymph Nodes , Operative Time , Prospective Studies , Recurrence , Survival Rate , Ureter , Urinary Bladder , Uterine Cervical Neoplasms , Vesicovaginal Fistula , Wounds and InjuriesABSTRACT
No abstract available.