Neural substrates of interactive musical improvisation: an FMRI study of 'trading fours' in jazz.

Interactive generative musical performance provides a suitable model for communication because, like natural linguistic discourse, it involves an exchange of ideas that is unpredictable, collaborative, and emergent. Here we show that interactive improvisation between two musicians is characterized by activation of perisylvian language areas linked to processing of syntactic elements in music, including inferior frontal gyrus and posterior superior temporal gyrus, and deactivation of angular gyrus and supramarginal gyrus, brain structures directly implicated in semantic processing of language. These findings support the hypothesis that musical discourse engages language areas of the brain specialized for processing of syntax but in a manner that is not contingent upon semantic processing. Therefore, we argue that neural regions for syntactic processing are not domain-specific for language but instead may be domain-general for communication.

The endowment effect can extend from self to mother: evidence from an fMRI study.

People typically demand more to part with goods they own than they would be willing to pay to acquire identical goods they do not own, a phenomenon known as the endowment effect [1-3]. Recently, a large body of behavioral research has suggested that the endowment effect may actually be a type of self-referent cognitive bias resulting from ownership of an object. However, the neural underpinnings of this effect are not well understood. In the present study, we used functional magnetic resonance imaging (fMRI) to explore whether brain activity can predict the extensibility of the endowment effect to items owned by another individual with a close relationship to the subject. Subjects were asked to decide whether to buy or sell their own or their mothers' possessions at various prices. Behavioral results showed an endowment effect not only for goods owned by the subjects, but also for goods owned by the subjects' mothers, providing evidence for the extensibility of the endowment effect. Neuroimaging data showed activation in the medial prefrontal cortex (MPFC) and insula in both ownership conditions. Also, MPFC activation was positively correlated with the behavioral indifference point in the sell-for-self and sell-for-mother conditions. Furthermore, psychophysiological interaction (PPI) analysis revealed that MPFC activation was accompanied by increased functional integration with insula and striatum. Together, these findings suggest that MPFC may play an important role in the extensibility of the endowment effect.