1.
Toxicol Lett
; 14(3-4): 189-94, 1982 Dec.
Article
in English
| MEDLINE
| ID: mdl-7167978
ABSTRACT
The inorganic pigments nickel rutile yellow and chrome rutile yellow were fed to groups of 15 male and 15 female rats each for 3 months at dietary levels of 0, 10, 100, 1000 and 10000 ppm, respectively. On an additional 5 animals each, levels of nickel and antimony or chromium and antimony in liver and kidneys, respectively, were measured after 1 and 2 months. Appearance, behaviour, food consumption, growth, mortality, haematological and clinical chemical data, organ weights, and gross and micromorphology of organs were not affected in any dose group. In livers and kidneys antimony median levels below 30 ppb were detectable only in the group of rats fed the highest level of 10000 ppm of the two pigments.
Subject(s)
Antimony/toxicity , Chromium Compounds , Chromium/toxicity , Coloring Agents/toxicity , Nickel/toxicity , Titanium/toxicity , Animals , Antimony/analysis , Body Weight/drug effects , Chromium/analysis , Female , Kidney/metabolism , Liver/metabolism , Male , Nickel/analysis , Rats , Rats, Inbred Strains , Sex Factors
2.
Zentralbl Arbeitsmed Arbeitsschutz Prophyl
; 28(6): 165-8, 1978 Jun.
Article
in German
| MEDLINE
| ID: mdl-664927