Subject(s)
Granulomatosis with Polyangiitis/diagnosis , Granulomatosis with Polyangiitis/drug therapy , Methylprednisolone/administration & dosage , Tuberculosis, Pulmonary/diagnosis , Antitubercular Agents/therapeutic use , Diagnosis, Differential , Dose-Response Relationship, Drug , Drug Administration Schedule , Female , Follow-Up Studies , Humans , Middle Aged , Recurrence , Risk Assessment , Severity of Illness Index , Treatment Outcome , Tuberculosis, Pulmonary/drug therapyABSTRACT
The side-effects of radiation therapy on the bronchial tree or on the mediastinum are seldom reported. In this setting, we report a case of sclerosing mediastinitis with bronchial stenosis discovered 1 yr after external radiotherapy for lung cancer. The patient was treated with a Dumont stent and has so far had an uneventful further course for up to 42 months. Bronchial stenosis related to mediastinal fibrosis after radiotherapy has not been reported previously.
Subject(s)
Adenocarcinoma/radiotherapy , Bronchial Diseases/etiology , Lung Neoplasms/radiotherapy , Mediastinitis/etiology , Mediastinitis/pathology , Radiation Injuries/complications , Adenocarcinoma/surgery , Bronchial Diseases/diagnosis , Bronchial Diseases/diagnostic imaging , Combined Modality Therapy , Constriction, Pathologic , Female , Fiber Optic Technology/methods , Humans , Lung Neoplasms/surgery , Middle Aged , Sclerosis , Tomography, X-Ray ComputedABSTRACT
The authors report a case of a black African patient who suffers from a chronic eosinophilic pneumonia. In view of the lack of precise reporting in the literature of such a case in black Africans, the initial difficulty of strictly excluding a parasitologic etiology is discussed. From the comparison of paraclinical and clinical data with those of the literature, the authors emphasize the close relationship between asthma and chronic eosinophilic pneumonia and the role of alveolar eosinophils in the physiopathology of that illness.
Subject(s)
Pulmonary Eosinophilia/diagnosis , Adult , Black or African American , Anti-Inflammatory Agents/therapeutic use , Black People , Chronic Disease , Democratic Republic of the Congo , Diagnosis, Differential , Humans , Lung Diseases, Parasitic/diagnosis , Male , Methylprednisolone/therapeutic use , Pulmonary Eosinophilia/drug therapy , Pulmonary Eosinophilia/ethnologyABSTRACT
The authors report an observation of Wegener's granulomatosis with pulmonary, bronchial, renal, cutaneous and sinusal involvement. Five years ago, the patient was referred to us because of bilateral diffuse pulmonary infiltrates of unknown origin. A corticotherapy was introduced at that time and a complete clearance of the pulmonary infiltrates was noted. Nineteen months after the treatment's withdrawal, the disease recurs with the reappearance of pulmonary infiltrates. Beyond these unusual clinical aspects, histological examination of the bronchial biopsies were of diagnostic value.
