How efficacious is the combination of substitute bone graft with autogenous bone graft in comparison with substitute bone graft alone in the horizontal bone gain? A systematic review and meta-analysis.

Background: A systematic review (SR) was conducted to answer the following focused question based on PICO strategy: In patients who were submitted to horizontal guided bone regeneration, "how efficacious is the combination of substitute bone graft with autogenous bone graft in comparison with substitute bone graft alone, in terms of bone gain?" Material and Methods: MEDLINE (PubMed), Scopus, Embase, Web of Science databases were searched, and hand searches were made up to June 2021, to find randomized clinical trials comparing the clinical effects of autogenous bone graft + substitute bone graft versus substitute bone graft alone in the treatment of horizontal guided bone regeneration. Results: Four trials representing 109 individuals were included. All studies included in this SR used allogeneic bone graft. The meta-analysis did not show any statistically significant difference between the groups, for horizontal bone gain at a distance of 0 mm (MD: -0.46; 95%CI: -1.03 - 0.11) or at a distance of 4 to 5 mm from the top of the crestal alveolar ridge (MD: 0.17; 95%CI: -1.08 - 1.42). Conclusions: Within limitations of this systematic review, it was concluded that the addition of autogenous bone graft to the allogeneic bone graft did not significantly increase the quantity of regenerated bone. Key words:Bone graft, bone regeneration, allograft.

Alveolar Ridge Preservation Using a Bovine derived Bone Graft in Association with Titanium Foil - A Prospective Case Series.

AIMS: To estimate the change in the alveolar ridge by means of a new alveolar ridge preservation (ARP) approach, using an anodized titanium foil (Tseal) associated with a bovine bone graft (BBG) by cone-beam computerized tomography. MATERIALS AND METHODS: Sixteen patients, each presenting one hopeless tooth, were selected and these teeth were carefully extracted. The alveolar socket was filled with BBG and the Tseal was trimmed and adapted to the bone crest. The primary outcome variable was the change in the alveolar dimension (AD) measurements between baseline (T1) and 6 months (T2) 1mm below the palatal bone. RESULTS: Imaging assessment of AD demonstrated a decreased value in all subjects. The absolute rate and percentage of absorption between T1 and T2 time point showed statistically significant differences. The mean AD varied from 9.88 ± 2.04 mm (T1) to 8.85 ± 1.92 mm (T2). On average, this ARP procedure maintained 89.55% ± 6.11% of the distance of between the buccal and palatal wall. No differences were observed between the maxilla and mandible (p greater than 0.05). CONCLUSION: The application of a bovine bone graft covered with Tseal resulted in clinically important horizontal preservation of the alveolar ridge at 6 months after extraction.

Impact of smoking on human bone apposition at different dental implant surfaces: a histologic study in type IV bone.

Smoking has adverse effects on peri-implant bone healing and can cause bone loss around successfully integrated implants placed on type IV bone. This study evaluated the influence of implant surface topography of microimplants retrieved from posterior maxilla of smokers after 2 months of unloaded healing. Seven partially edentulous patients received 2 microimplants (machined and sandblasted acid-etched surface) each during conventional implant surgery. Histometric evaluation showed that the mean bone to implant contact was 10.40 +/- 14.16% and 22.19 +/- 14.68% to machined and sandblasted acid-etched surfaces, respectively (P < .001). These data suggest that the sandblasted acid-etched surface presented better results than the machined surface after a short healing time in smokers.