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Top Companion Anim Med ; 37: 100357, 2019 Dec.
Article in English | MEDLINE | ID: mdl-31837753

ABSTRACT

Inflammatory mammary carcinoma (IMC) is a rare and aggressive variant of a malignant mammary tumor. The present report describes the case of a male dog with clinical and histopathologic signs suggestive of IMC. The patient was presented to our clinic with painful and erythematous skin over the ventral abdomen, as well as preputial and left hind limb edema apparently associated with ill-defined nodules in the caudal mammary region. Cytologic examination of the nodules suggested the presence of a malignant epithelial tumor. Histopathology revealed anaplastic carcinoma with embolization in the dermal lymphatics. Immunohistochemistry showed cyclooxygenase-2 and E-cadherin expression in the neoplastic cells. The patient died 35 days after initial evaluation. To the best of our knowledge, this is the first published case describing IMC in a male dog.


Subject(s)
Carcinoma/veterinary , Dog Diseases/pathology , Mammary Neoplasms, Animal/pathology , Animals , Cadherins/metabolism , Cyclooxygenase 2/metabolism , Dogs , Embolism/veterinary , Immunohistochemistry/veterinary , Lymph Nodes/cytology , Male
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