ABSTRACT
Ideally, our clinical practices and decisions should be based on evidence derived from randomized clinical trials. Yet, we often have to determine the potential side effects (including interactions) of drugs that we prescribed using other level of evidence; clinical trials being obviously not appropriate for such situations. Results from observational studies published in 2016 should be of interest to primary care physicians. In this review, we present six of them. Once the limitations of these non-interventional studies acknowledged, primary care physicians should consider these results and be particularly attentive when prescribing these drugs.
Dans l'idéal, nos pratiques et décisions sont guidées sur la base d'évidences issues d'études cliniques randomisées. Cependant, nous devons fréquemment juger des possibles effets indésirables (y inclus interactions) des médicaments que nous prescrivons sur la base d'autres types d'informations, les essais cliniques n'étant pour des raisons évidentes pas réalisables. Les résultats de plusieurs études observationnelles publiées en 2016 dans ce domaine devraient attirer notre attention. Nous présentons ici six d'entre elles. Une fois les limites inhérentes à ce type d'étude considérées, ces résultats nous invitent à être particulièrement vigilants lors de nos prescriptions.
Subject(s)
General Practice/trends , Iatrogenic Disease , Intention , Internal Medicine/trends , Drug-Related Side Effects and Adverse Reactions/epidemiology , Drug-Related Side Effects and Adverse Reactions/etiology , General Practice/methods , Humans , Iatrogenic Disease/epidemiology , Internal Medicine/methods , Practice Patterns, Physicians'/statistics & numerical data , Practice Patterns, Physicians'/trends , Treatment OutcomeABSTRACT
People are more and more looking for adventures and discovery of unusual locations. Journeys to high altitude and scuba diving are part of these activities and their access has become easier for a lot of people not necessarily experienced with their dangers. The general practitioner will have to be able to deliver some advices and recommendations to his patients about the risks related to these activities and their ability to practice them. He will also have to deliver some certificates of medical fitness to dive. This paper proposes a brief review of the most important medical aspects to know about high altitude and scuba diving.
