ABSTRACT
This article presents the results of the analysis of data from patients over 75 years of age from a multidisciplinary hospital with cardiovascular disease and comorbid conditions. Pharmacotherapy of gerontological patients with multiple risk factors for falls was analysed in terms of the presence of polypragmasy and drug-drug interactions hazardous to the risk of falls. In the group of patients who experienced a fall in hospital compared to patients without a fall, the prescription lists audit showed a predominance of medicines (drugs) and drug combinations compromised by an increased risk of this serious adverse event. An audit of prescriptions of patients at increased risk of falls as a means of combating polypharmacy and identifying drugs that may cause falls can be conducted using the «Traffic light classification of FRIDs¼ and drug checkers to identify clinically relevant combinations. The use of these clinical and pharmacological tools can improve the quality and safety of medical care in a hospital setting.
Subject(s)
Accidental Falls , Polypharmacy , Humans , Aged , Accidental Falls/prevention & control , Risk FactorsABSTRACT
An increasingly greater fraction of the general population is getting involved in the immunization program. However, conditions of individual subjects are not always properly evaluated prior to immunization. The clinical case reported below demonstrates the difficulty of diagnostic examination of patients with Graves disease (toxic goiter), endocrine ophthalmopathy, and post-immunization reaction.
Subject(s)
Graves Disease/diagnosis , Influenza Vaccines/adverse effects , Vaccination/adverse effects , Adult , Autoimmunity/drug effects , Diagnosis, Differential , Follow-Up Studies , Graves Disease/blood , Graves Disease/chemically induced , Graves Disease/immunology , Humans , Male , Thyroid Hormones/bloodABSTRACT
According to estimates of WHO experts cases with diagnosed cardiomyopathy account for 40-60 per 100,000. Restrictive cardiopathy (RCP) is encountered in 5% of all the diagnosed cases of cardiomyopathy. Two patients (a mother and her daughter) with suspected of family RCP were examined using ECG, Holter ECG monitoring, echo-CG, histological tests, x-ray, blood biochemical tests. Echo-CG was most informative for verification of RCP diagnosis. The daughter had edema, enlarged liver, arterial hypertension, cardiac arrhythmia. The mother had arrhythmia, dyslipidemia. Based on the above symptoms, the patients received combined drug therapy with positive results.
