ABSTRACT
It has been suggested that hearing impairment (HI) is one of the extra-articular features of rheumatoid arthritis (RA). Nevertheless, the prevalence and nature of HI in RA is still uncertain. The objectives were to study hearing function in patients with RA using audiometric tests and to examine whether HI correlates with autoantibodies. Hearing functions were investigated in 43 consecutive RA patients and 23 control subjects (less than 60 years old). Their sera were evaluated for the presence of rheumatoid factor (RF), anti-cyclic citrullinated peptide (anti-CCP), and anti-mutated citrullinated vimentin (anti-MCV) antibodies. HI was observed in 46.5 % of RA patients and in 30.4 % of control subjects, p = 0.32. HI was characterized as sensorineural in 80 and 85.7 % of RA patients and control subjects with HI, respectively, p = 1.00. RA patients had a worse hearing threshold for air conduction at 6 kHz in the right ear (p = 0.019) and had a decreased amplitude of otoacoustic emissions (OAEs) at 2 kHz bilaterally (p = 0.04) compared with control subjects. In the RA group, patients with and without HI were 80 and 34.78 % anti-CCP positive, respectively, p = 0.008. RA patients with and without HI were 85 and 43.48 % anti-MCV positive, respectively, p = 0.013. HI in RA patients was mainly sensorineural and was associated with anti-CCP and anti-MCV antibodies.
Subject(s)
Arthritis, Rheumatoid/immunology , Autoantibodies/blood , Hearing Loss/immunology , Adult , Arthritis, Rheumatoid/blood , Arthritis, Rheumatoid/complications , Female , Hearing Loss/blood , Hearing Loss/complications , Humans , Male , Middle Aged , Peptides, Cyclic/immunology , Rheumatoid Factor/blood , Vimentin/immunologyABSTRACT
Introdução: O rinoscleroma é uma doença nasal granulomatosa rara, causada pela bactéria klebsiella rhinoscleromatis. O nariz representa a região primária de ocorrência. O linfoma não-Hodgkin nasal é uma rara neoplasia maligna, podendo ser do tipo T ou B. O rinoscleroma e o linfoma nasal não-Hodgkin apresentam como principal sintoma a obstrução nasal, e fazem parte do diagnóstico diferencial das granulomatoses nasais. Objetivo: Relatar a associação de rinoscleroma e linfoma não-Hodgkin nasal em um mesmo paciente, destacando a importância do diagnóstico diferencial das granulomatoses nasais. Relato do Caso: Paciente do sexo feminino, 49 anos, atendida com obstrução nasal progressiva há um mês. A rinoscopia evidenciava lesão aspecto papilomatoso em meato médio esquerdo. A imunohistoquímica confirmou rinoscleroma. A paciente foi corretamente tratada com remissão total da lesão. Dez meses após retornou com mesmos sintomas, mas histologia confirmou linfoma não-Hodgkin. Comentários Finais: Ambas as patologias podem causar sintomas nasais graves e complicações. O diagnóstico precoce possibilita a instituição do tratamento adequado e favorece o prognóstico. O estudo imunohistoquímico foi fundamental para a diferenciação diagnóstica.
Introduction: Rhinoscleroma, a rare nasal granulomatous disease, is caused by Klebsiella rhinoscleromatis. The nose is the primary occurrence region. Nasal non-Hodgkin lymphoma is a rare cancer, and could be of T or B type. The rhinoscleroma and the nasal non-Hodgkin lymphoma present with nasal obstruction as the main symptom, and are part of the nasal granulomatosis differential diagnosis. Objective: To report the association of rhinoscleroma and non-Hodgkin lymphoma in the same patient, by remarking the importance of the nasal granulomatosis' differential diagnosis. Case Report: A forty-nine year old female patient that appeared with a one-month progressive nasal obstruction. Rhinoscopy showed papillomatous feature lesion in left middle meatus. The immunohistochemical analysis confirmed rhinoscleroma. The patient was duly treated with total remission of the lesion. Ten months after, she returned with the same symptoms, but the histologic study confirmed non-Hodgkin lymphoma. Final Comments: Both pathologies may cause more severe nasal symptoms and complications. The early diagnostic enables the choice for the right treatment and contributes for the prognosis. The immunohistochemical study was essential for the diagnostic differentiation.
Subject(s)
Humans , Female , Adult , Nose Diseases/pathology , Lymphoma, Non-Hodgkin/diagnosis , Lymphoma, Non-Hodgkin/physiopathology , Nasal Obstruction/etiology , Rhinoscleroma , ImmunohistochemistryABSTRACT
Introdução: Otite média com efusão (OME) é uma das doenças mais comuns na infância. Manifestações clínicas variam do prejuízo na fala ao déficit no aprendizado. O diagnóstico deve ser feito, principalmente, pelo exame físico e timpanometria. O tratamento da OME pode ser clínico ou cirúrgico, inserindo-se um tubo de ventilação. Objetivo: Avaliar o seguimento de pacientes com OME submetidos à colocação de tubo de ventilação comparando-se os achados audiométricos pré e pós-operatórios. Método: Crianças com OME e falha no tratamento clínico foram submetidas à timpanostomia e colocação de tudo de ventilação. A audiometria obtida no pré-operatório foi comparada à solicitada durante o acompanhamento, entre seis e doze meses após a cirurgia, posteriormente à extrusão do tubo. Resultados: O Limiar de Reconhecimento de Fala passou de um valor médio de 28,75 dB para 13 dB. Conclusões: As crianças submetidas à colocação de tubo de ventilação apresentaram significativa melhora audiométrica após a cirurgia. Visto que os dados deste estudo foram obtidos de exames objetivos, acreditamos que esta seja uma excelente forma de avaliar os resultados cirúrgicos de pacientes submetidos à colocação de tubo de ventilação.
Introduction: Otitis media with effusion (OME) is one of the most common diseases in the childhood. Clinical manifestations vary from speech damage to learning deficit. The diagnosis must be made, mainly, through the physical exam and tympanometry. The treatment of OME may be clinical or surgical, with a vent tube. Objective: To evaluate the follow-up of patients with OME submitted to the placing of vent tube and compare the pre- and postoperative audiometric findings. Method: Children with OME and failure in the clinical treatment were submitted to tympanometry and placing of vent tube. The audiometry obtained in the postoperative period was compared with that requested during follow-up, between six and twelve months after surgery, subsequent to the tube extrusion. Results: The Speech Recognition Threshold exceeded an average value of 28.75 dB to 13 dB. Conclusions: The children submitted to the placement of the vent tube presented a significant audiometric improvement after the surgery. Since the data in this study were obtained from objective exams, we believe this is an excellent way to evaluate the surgical results of patients submitted to the placement of the vent tube.
Subject(s)
Humans , Child , Audiometry , Child , Middle Ear Ventilation , Otitis Media/surgery , Follow-Up StudiesABSTRACT
Introdução: A presença de dente supranumerário ou ectópico não é fato incomum, sendo estimado ocorrer em 1% da população geral. Contudo, um dente em cavidade nasal constitui-se em evento raro, independente da etiologia. Objetivo: Relatar um caso de dente em fossa nasal cuja etiologia não foi traumática nem iatrogênica. Relato de Caso: Paciente jovem apresentou imagem radiopaca em fossa nasal quando em propedêutica odontológica. Durante investigação otorrinolaringológica, verificou-se tratar-se se dente, a despeito da inexistência de qualquer trauma. Foi realizado tratamento cirúrgico sem intercorrências. Comentários Finais: A presença de dente em fossa nasal, apesar de infrequente, deve receber atenção especial. O triângulo perigoso da face é local potencial de complicações, portanto, a abordagem deve ser cirúrgica, mesmo que o paciente esteja assintomático.
Introduction: The presence of ectopic supernumerary tooth is not an uncommon fact, and the estimate is that 1% of the population is affected. However, a tooth in nasal cavity is a rare event, independently of the etiology. Objective: To report a case of a tooth in nasal cavity whose etiology is neither traumatic and nor iatrogenic. Case report: The young patient presented with a radiopaque image in nasal cavity during dental propedeutics. Upon otorhinolaryngological exams, a tooth was identified, in spite of no existence of any trauma. Surgical treatment was carried out without complications. Final Comments: The presence of tooth in nasal cavity, in spite of being uncommon, must be given special attention. The dangerous triangle of the face is a potential place of complications, therefore, the approach must be surgical even in asymptomatic patients.
Subject(s)
Humans , Male , Child , Nasal Cavity/surgery , Dentition, Permanent , Tooth Migration/surgery , Tooth Migration/complications , Tooth Migration/etiology , Physiological PhenomenaABSTRACT
Relato do Caso: Apresentamos um caso de pneumatização bilateral dos cornetos inferiores, condição muito rara, clinicamente manifesta por obstrução. A abordagem cirúrgica foi cuidadosamente planejada e conduzida, devido a uma grande comunicação entre os seios maxilares e as conhas inferiores bolhosas.
Case Report: We present one case of bilateral pneumatization of the inferior turbinates, a very rare condition, clinically manifested by obstruction. The surgical approach was carefully planned and carried out, due to a wide communication between the maxillary sinuses and the bobble-like inferior turbinates.
Subject(s)
Humans , Male , Adolescent , Hyaline Cartilage/surgery , Turbinates/surgery , Nasal Obstruction/etiologyABSTRACT
Este estudo tem como objetivo avaliar a prevalência de lesões de cabeça e pescoço em mulheres, frente aos inquéritos policiais registrados como lesão corporal e maus-tratos na Delegacia de Defesa da Mulher de Araçatuba, São Paulo, Brasil, no ano de 2002. Foram totalizados 204 inquéritos policiais no ano de 2002, e destes extraídos 33 laudos periciais referentes aos crimes de lesões corporais e maus-tratos em mulheres. Analisou-se nos laudos médicos da perícia, aspectos relativos à idade das vítimas e local das lesões por elas apresentadas na ocasião do exame. Os resultados encontrados revelam que as agressões ocorrem em faixas etárias diversas, com predominância na infância e adolescência. Além disso, ocorreu a maior prevalência de lesões na região da cabeça e pescoço, área de atuação do cirurgião-dentista que necessita estar preparado para atender, entre outros, o paciente vítima de violência.
This study aimed to evaluate the prevalence of head and neck injuries in females based on complaints registered as bodily harm or cruel and unusual punishment at the Women's Defense Precinct in Araçatuba, São Paulo State, Brazil, in 2002. A total of 204 police inquiries were conducted in 2002, resulting in 33 police reports of bodily harm and cruel and unusual punishment to females. The police reports were examined as to victim's age and site of injury. The results showed that injuries are inflicted on various age brackets, with a higher prevalence in children and adolescents. In addition, the highest prevalence of injuries was in the head and neck, encompassing the area where dentists work and where they should be prepared to treat victims of such violence.
Subject(s)
Female , Humans , Wounds and Injuries/epidemiology , Battered Women/statistics & numerical data , Domestic Violence/statistics & numerical data , Brazil/epidemiology , Wounds and Injuries/etiology , Injury Severity Score , Battered Women/legislation & jurisprudence , Prevalence , Crime Victims/statistics & numerical dataABSTRACT
This study aimed to evaluate the prevalence of head and neck injuries in females based on complaints registered as bodily harm or cruel and unusual punishment at the Women's Defense Precinct in Araçatuba, São Paulo State, Brazil, in 2002. A total of 204 police inquiries were conducted in 2002, resulting in 33 police reports of bodily harm and cruel and unusual punishment to females. The police reports were examined as to victim's age and site of injury. The results showed that injuries are inflicted on various age brackets, with a higher prevalence in children and adolescents. In addition, the highest prevalence of injuries was in the head and neck, encompassing the area where dentists work and where they should be prepared to treat victims of such violence.