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4.
Presse Med ; 32(31): 1455-6, 2003 Sep 27.
Article in French | MEDLINE | ID: mdl-14534476

ABSTRACT

INTRODUCTION: Hypertrophic osteoarthropathy (HOA) is a syndrome associating hippocratic fingers, arthropathy and periostosis of long bones. Currarino's disease, considered at present as a clinical form of primary HOA, is characterized by the absence of pachydermia. OBSERVATION: A 24-year-old Caucasian man, consulted for a painful swelling of both ankles that had developed over the past year. Clinical examination revealed hippocratic fingers without pachydermia. The ankles were swollen. The X-rays showed periosteal apposition and an acro-osteolysis. In view of this triad: arthropathy, hippocratic fingers and periostosis, primary HOA without cutaneous involvement or Currarino's disease was diagnosed. The search for a secondary cause remained negative. Clinical improvement was obtained after 15 months with non-steroidal anti-inflammatory drugs (NSAID) and colchicine. COMMENTS: Although exceptional, primary HOA without cutaneous involvement is a genetic disease which must not be ignored.


Subject(s)
Osteoarthropathy, Primary Hypertrophic/diagnostic imaging , Adult , Humans , Male , Radiography
5.
Rev Mal Respir ; 16(5): 846-8, 1999 Nov.
Article in French | MEDLINE | ID: mdl-10612158

ABSTRACT

Bronchopulmonary involvement is uncommon in ulcerative colitis. Bronchiectasis is a rare manifestation of the disease. We report a case of a 65-year-old patient with ulcerative colitis in whom we diagnosed bronchiectasis. The evidence of a relationship between bronchiectasis and ulcerative colitis was established on the basis of 3 criteria: the late occurrence of bronchiectasis in a patient without pulmonary history, their appearance after the ulcerative colitis developed and their improvement after inhaled corticosteroid treatment. This observation points out that ulcerative colitis investigations should be extended to the respiratory structures. The respiratory involvement is not always concomitant with the bowel disease. This observation suggests the efficiency of the inhaled corticosteroids in this disease.


Subject(s)
Bronchiectasis/etiology , Colitis, Ulcerative/complications , Aged , Anti-Inflammatory Agents/administration & dosage , Beclomethasone/administration & dosage , Bronchiectasis/diagnostic imaging , Bronchiectasis/drug therapy , Follow-Up Studies , Humans , Male , Radiography, Thoracic , Respiratory Therapy , Time Factors , Tomography, X-Ray Computed
6.
Rev Med Interne ; 19(12): 917-20, 1998 Dec.
Article in French | MEDLINE | ID: mdl-9887460

ABSTRACT

INTRODUCTION: Disseminated tuberculosis, i.e., tuberculosis involving lung, liver, spleen, bone marrow and lymph nodes is rare (2.8%), particularly when immunocompromised diathesis is lacking. EXEGESIS: We report three cases of disseminated tuberculosis confirmed by bacteriology or histology, which occurred in non-immunocompromised patients. Disease evolution under antituberculous treatment was favorable in two cases and fatal in the third one. CONCLUSION: Disseminated tuberculosis must be suspected when miliary pulmonary lesions are associated with hematologic abnormalities, even in non-immunocompromised host. Early treatment is mandatory to avoid fatal outcome.


Subject(s)
Immunocompetence , Tuberculosis, Miliary/diagnosis , Tuberculosis, Miliary/drug therapy , Adult , Antitubercular Agents/therapeutic use , Drug Therapy, Combination , Humans , Male , Middle Aged , Tuberculosis, Hepatic/etiology , Tuberculosis, Lymph Node/etiology , Tuberculosis, Miliary/complications , Tuberculosis, Pulmonary/etiology , Tuberculosis, Splenic/etiology
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