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Ultrasound Med Biol ; 39(12): 2295-307, 2013 Dec.
Article in English | MEDLINE | ID: mdl-24120412

ABSTRACT

Prosthetic grafts are used for the treatment of peripheral arterial disease. Re-stenosis in the distal anastomosis of these grafts is a common reason for graft occlusion. The role of local hemodynamics in development of neo-intimal hyperplasia is well known. A new graft design has been proposed for the induction of optimized spiral flow in the host vessel. The secondary flow motions induced by this graft were compared with those of a control device. Both types of grafts were connected with vessel mimic and positioned in ultrasound flow phantoms with identical geometry. Constant flow rates were applied. Data collected in the cross-sectional view distal from the graft outflow and dual-beam vector Doppler was applied to create 2-D velocity maps. A single-spiral flow pattern was found for the flow-modified graft, and double or triple spirals for the control graft. In-plane maximum velocity was greater for the flow-modified graft than for the control device.


Subject(s)
Arteries/physiology , Arteries/surgery , Blood Flow Velocity/physiology , Blood Vessel Prosthesis , Image Interpretation, Computer-Assisted/methods , Models, Cardiovascular , Ultrasonography, Doppler/methods , Arteries/diagnostic imaging , Computer Simulation , Equipment Failure Analysis , Humans , Phantoms, Imaging , Prosthesis Design , Ultrasonography, Doppler/instrumentation
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