ABSTRACT
Malakoplakia is an uncommon inflammatory condition usually affecting the genitourinary tract, which has been associated with infections, tumors, and immunocompromised states. The condition has been reported in many different organs and it may rarely involve the skin. We describe a case of an isolated perianal cutaneous malakoplakia in an immunocompetent 23-year-old Syrian male.
Subject(s)
Anus Diseases/diagnosis , Malacoplakia/diagnosis , Anti-Bacterial Agents/therapeutic use , Anus Diseases/drug therapy , Anus Diseases/pathology , Anus Diseases/surgery , Anus Neoplasms/diagnosis , Ascorbic Acid/therapeutic use , Ciprofloxacin/therapeutic use , Combined Modality Therapy , Condylomata Acuminata/diagnosis , Diagnostic Errors , Drug Therapy, Combination , Humans , Immunocompetence , Macrophages/physiology , Malacoplakia/drug therapy , Malacoplakia/pathology , Malacoplakia/surgery , Male , Recurrence , Young AdultABSTRACT
The case presented in the article "Severe retention hyperkeratosis occurring with Susac syndrome" in October 2010 of DOJ (16:10) is very dramatic. Although it was implied in the article, the authors did not state that this is actually Dermatosis neglecta, the same entity reported by Poskitt et al 15 years ago. The description of the case in the article, histopathology, mechanism of pathogenesis, and treatment are consistent with Dermatosis neglecta, only with a different name.
