ABSTRACT
New macrolide antibiotic, roxithromycin (erythromycin--like group), was tested in treatment of chlamydial genital infection in women. In comparison with doxycycline, roxithromycin showed higher clinical efficiency with fewer sides effects.
Subject(s)
Anti-Bacterial Agents/therapeutic use , Chlamydia Infections/drug therapy , Chlamydia trachomatis , Genital Diseases, Female/drug therapy , Roxithromycin/therapeutic use , Adult , Doxycycline/therapeutic use , Female , HumansABSTRACT
Mechanism of estrogens effect on bone metabolism in relation to postmenopausal period is discussed. An emphasis is on multiple effects of estrogens as both systemic and local factors. A role of progesterone and other gestagens in the process of bone remodelling is also stressed.
Subject(s)
Bone and Bones/metabolism , Estrogens/physiology , Osteoporosis, Postmenopausal/metabolism , Aged , Estrogens/therapeutic use , Female , Humans , Middle Aged , Osteoporosis, Postmenopausal/prevention & controlABSTRACT
68 women with sterility treatment were tested. Among 13 of them (20%) presence of chlamydial antibodies was found. Hormonal profile was estimated. In a group of women with positive serologic reaction increased concentration of prolactin was found.
Subject(s)
Chlamydia Infections/diagnosis , Chlamydia trachomatis , Infertility/microbiology , Adult , Antibodies, Bacterial/analysis , Chlamydia Infections/blood , Chlamydia trachomatis/immunology , Female , Humans , Infertility/blood , Infertility/therapy , Prolactin/blood , Serologic TestsABSTRACT
Urinary steroid profiling by means of Capillary gas chromatography in postmenopausal women was detected. Glass capillary columns, OV-1, were used. Our results show that there is a rise of extraction of etiocholanolone (ET) in case of postmenopausal women in compare with androsterone (AN). The ratio ET/AN confirms the above results.
