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Hematol Oncol Clin North Am ; 32(4): 619-628, 2018 Aug.
Article in English | MEDLINE | ID: mdl-30047415

ABSTRACT

This article summarizes the recent development in the field of front-line unrelated donor transplantation for idiopathic aplastic anemia. The role of unrelated donor transplantation in the algorithm of pediatric aplastic anemia is reviewed and incorporates upfront unrelated donor transplantation. Newer strategies to delineate which children should receive immune suppression or transplantation are also discussed.


Subject(s)
Algorithms , Anemia, Aplastic , Hematopoietic Stem Cell Transplantation , Unrelated Donors , Anemia, Aplastic/immunology , Anemia, Aplastic/pathology , Anemia, Aplastic/therapy , Child , Graft vs Host Disease/immunology , Graft vs Host Disease/pathology , Graft vs Host Disease/prevention & control , Humans , Infant , Transplantation, Homologous
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