ABSTRACT
Madelung disease is rare, and characterised by accumulation of fatty non-encapsulated tissue in the head, neck, shoulders, and upper extremities. The aetiology is not completely known, but the association with alcohol intake is clear. We present a neglected case that was associated with bilateral asymmetrical gynaecomastia. To the best of our knowledge, this is a pattern of involvement not previously reported. The treatment of choice is lipectomy for severe cases and liposuction for less extensive accumulations of fat.
Subject(s)
Genital Diseases, Male/diagnosis , Gynecomastia/diagnosis , Lipomatosis, Multiple Symmetrical/diagnosis , Scrotum/physiopathology , Alcoholism/complications , Alcoholism/diagnosis , Follow-Up Studies , Genital Diseases, Male/complications , Gynecomastia/complications , Gynecomastia/surgery , Humans , Lipectomy/methods , Lipomatosis, Multiple Symmetrical/complications , Lipomatosis, Multiple Symmetrical/surgery , Male , Mastectomy/methods , Middle Aged , Rare Diseases , Risk Assessment , Severity of Illness Index , Smoking/adverse effects , Treatment OutcomeABSTRACT
PURPOSE: This case report describes a rare and aggressive ameloblastic carcinoma that infiltrated the mandible in a "honeycomb" pattern. METHODS: A total mandibulectomy with bilateral modified neck dissection was followed by primary reconstruction with a single free vascularised fibula flap. RESULTS: The postoperative course was uneventful. The one year follow-up revealed no signs of recurrent tumour or metastases. Nine months later distant metastases occurred in the lung. CONCLUSION: Ameloblastic carcinoma is a highly malignant lesion, which requires aggressive therapy. Prognosis is poor. Further reporting of ameloblastic carcinoma is encouraged.
