ABSTRACT
Abuse of ecstasy is the second most frequent cause of acute liver failure in young adults less than 25 years of age. Typically, the disease has an acute onset and runs a severe course with jaundice, coagulopathy and a tendency to hypoglycemia. Transplantation of the liver may be required. The histological characteristics are not yet sufficiently known. We report the case of a 17-year-old patient with a clinically severe, protracted course, presenting a giant cell hepatitis in the liver biopsy.
Subject(s)
Chemical and Drug Induced Liver Injury/diagnosis , Giant Cells/pathology , Hallucinogens/toxicity , Jaundice/etiology , N-Methyl-3,4-methylenedioxyamphetamine/toxicity , Substance-Related Disorders/complications , Adolescent , Chemical and Drug Induced Liver Injury/pathology , Humans , Jaundice/pathology , Liver/pathology , Liver Function Tests , Male , Substance-Related Disorders/pathologyABSTRACT
Clinically silent adrenal masses (incidentaloma) are incidentally discovered lesions, when noninvasive imaging methods (USG, CT, MRI) are performed for reasons other than known or suspected adrenal disease. Most studies report on a prevalence of adrenal incidentaloma range between 1% and 10% in radiological series. Between 1994 and 1999 we observed in our Department 57 patients with incidentalomas of adrenal glands. After endocrinological evaluation silent Cushing's syndrome was found in 2 cases (3.5%). Fifty two patients were qualified for surgery. Adrenocortical adenoma was diagnosed in 73.1%; adrenocortical carcinoma in 7.7%; pheochromocytoma in 7.7% and less frequent adrenal lesions in 11.5%. All adrenal carcinomas and malignant pheochromocytomas (11.5%) were found in tumors with diameter over 4 cm.
Subject(s)
Adrenal Cortex Neoplasms/diagnostic imaging , Adrenal Cortex Neoplasms/epidemiology , Adrenal Cortex Neoplasms/pathology , Adrenocortical Adenoma/diagnostic imaging , Adrenocortical Adenoma/epidemiology , Adrenocortical Adenoma/pathology , Adrenocortical Carcinoma/diagnostic imaging , Adrenocortical Carcinoma/epidemiology , Adrenocortical Carcinoma/pathology , Adult , Aged , Diagnosis, Differential , Female , Humans , Incidence , Male , Middle Aged , Pheochromocytoma/diagnostic imaging , Pheochromocytoma/epidemiology , Pheochromocytoma/pathology , Poland/epidemiology , RadiographyABSTRACT
BACKGROUND: The isolated longstanding hypochromic hyposideremic anemia can be a unique symptom of the jejunal tumor. CASE REPORT: The authors present a case of 43-year-old woman with small intestine cancer, which manifested as longstanding anemia, decreased serum iron and remained undiagnosed over a period of several years. Special attention has been paid to the problem of adequate diagnostic procedure for disclosing the latent small intestine tumor.
