ABSTRACT
Os autores estudaram 31 pacientes portadores de tinhas crural, do corpo e do pe interdigital, tratados com 100 mg de itraconazol, administrados junto com o almoco, durante 15 dias. Foram realizadas 3 avaliacoes clinicas e micologicas: no pre-tratamento, no final do tratamento e 2 semanas apos o tratamento. O itraconazol mostrou-se eficaz para o tratamento das dermatofitoses estudadas, na dose empregada, com 100 por cento de cura micologica. Em relacao a evolucao clinica, houve diminuicao estatistica significante (teste de Friedman-p < 0.001) dos sinais e sintomas avaliados. Nao foi observada ocorrencia de efeitos colaterais
Subject(s)
Adolescent , Adult , Middle Aged , Humans , Male , Female , Antifungal Agents/therapeutic use , Tinea/diagnosis , Tinea/therapy , Ergosterol/biosynthesis , Tinea Pedis/therapyABSTRACT
The authors studied 31 patients with Tinea cruris, corporis or pedis interdigital. The patients were treated with 100 mg of itraconazole, once a day, during the lunch, for 15 days. Mycological and clinical evaluations were performed at the pre-treatment, by the end of treatment and 2 weeks after finishing the treatment. The results showed that itraconazole is effective for the treatment of dermatophytosis, at the studied posology, with 100% of mycological cure. Clinical evaluation showed a significant reduction (Friedman test--p less than 0.001) of signs and symptoms.
